Association between markers of cardiovascular risk and clinical parameters of periodontitis
INTRODUCTION: Periodontal disease is an inflammatory response to bacteria that reside in the gum tissue and can have systemic repercussion. OBJECTIVE: The aim of this study was to assess the relationship between periodontitis and markers of cardiovascular risk. MATERIAL AND METHOD: Ninety selected patients were assigned into two groups in accordance with their levels of probing pocket depth (PPD) and Clinical Attachment Level (CAL): control group, n= 45 (< 4 sites with PPD ≥ 4.0 mm and CAL ≥ 3.0 mm) and case group, n= 45 (≥ 30% of sites with PPD ≥ 4.0 mm and CAL ≥3.0 mm). Plasma concentrations of C-reactive protein, high sensitive CRP, high-density lipoproteins (HDL-c) and electronegative low density lipoproteins (LDL) were assessed in all participants. Data from medical history and socioeconomic level were also collected from patients. RESULT: Plasma levels of HDL-c were lower in subjects with periodontal disease (p = 0.016) and were inversely associated with the number of sites with PPD ≥ 3 mm (rho= -0.325) and number of sites with PPD ≥ 3 mm and CAL ≥ 3 mm (rho= -0.216). These associations remained significant after adjustments for dental plaque and smoking using Univariate Analysis of Covariance (p < 0.05). Adjusted odds ratio between periodontal disease and levels of HDL-c was 0.94 (CI95% 0.88-0.99) after adjusting for age, smoking and dental plaque. Other investigated markers of cardiovascular risk were not related to periodontal disease. CONCLUSION: Clinical parameters of periodontitis were inversely associated with plasma concentrations of HDL-c.
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Universidade Estadual Paulista Júlio de Mesquita Filho
2013
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oai:scielo:S1807-257720130005000042013-11-08Association between markers of cardiovascular risk and clinical parameters of periodontitisDomingues,José Eduardo GomesVettore,Mario ViannaLima,Emerson Silva Periodontal diseases HDL-c coronary heart disease cardiovascular risk INTRODUCTION: Periodontal disease is an inflammatory response to bacteria that reside in the gum tissue and can have systemic repercussion. OBJECTIVE: The aim of this study was to assess the relationship between periodontitis and markers of cardiovascular risk. MATERIAL AND METHOD: Ninety selected patients were assigned into two groups in accordance with their levels of probing pocket depth (PPD) and Clinical Attachment Level (CAL): control group, n= 45 (< 4 sites with PPD ≥ 4.0 mm and CAL ≥ 3.0 mm) and case group, n= 45 (≥ 30% of sites with PPD ≥ 4.0 mm and CAL ≥3.0 mm). Plasma concentrations of C-reactive protein, high sensitive CRP, high-density lipoproteins (HDL-c) and electronegative low density lipoproteins (LDL) were assessed in all participants. Data from medical history and socioeconomic level were also collected from patients. RESULT: Plasma levels of HDL-c were lower in subjects with periodontal disease (p = 0.016) and were inversely associated with the number of sites with PPD ≥ 3 mm (rho= -0.325) and number of sites with PPD ≥ 3 mm and CAL ≥ 3 mm (rho= -0.216). These associations remained significant after adjustments for dental plaque and smoking using Univariate Analysis of Covariance (p < 0.05). Adjusted odds ratio between periodontal disease and levels of HDL-c was 0.94 (CI95% 0.88-0.99) after adjusting for age, smoking and dental plaque. Other investigated markers of cardiovascular risk were not related to periodontal disease. CONCLUSION: Clinical parameters of periodontitis were inversely associated with plasma concentrations of HDL-c.info:eu-repo/semantics/openAccessUniversidade Estadual Paulista Júlio de Mesquita FilhoRevista de Odontologia da UNESP v.42 n.5 20132013-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772013000500004en10.1590/S1807-25772013000500004 |
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Domingues,José Eduardo Gomes Vettore,Mario Vianna Lima,Emerson Silva |
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Domingues,José Eduardo Gomes Vettore,Mario Vianna Lima,Emerson Silva Association between markers of cardiovascular risk and clinical parameters of periodontitis |
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Domingues,José Eduardo Gomes Vettore,Mario Vianna Lima,Emerson Silva |
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Domingues,José Eduardo Gomes |
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Association between markers of cardiovascular risk and clinical parameters of periodontitis |
title_short |
Association between markers of cardiovascular risk and clinical parameters of periodontitis |
title_full |
Association between markers of cardiovascular risk and clinical parameters of periodontitis |
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Association between markers of cardiovascular risk and clinical parameters of periodontitis |
title_full_unstemmed |
Association between markers of cardiovascular risk and clinical parameters of periodontitis |
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association between markers of cardiovascular risk and clinical parameters of periodontitis |
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INTRODUCTION: Periodontal disease is an inflammatory response to bacteria that reside in the gum tissue and can have systemic repercussion. OBJECTIVE: The aim of this study was to assess the relationship between periodontitis and markers of cardiovascular risk. MATERIAL AND METHOD: Ninety selected patients were assigned into two groups in accordance with their levels of probing pocket depth (PPD) and Clinical Attachment Level (CAL): control group, n= 45 (< 4 sites with PPD ≥ 4.0 mm and CAL ≥ 3.0 mm) and case group, n= 45 (≥ 30% of sites with PPD ≥ 4.0 mm and CAL ≥3.0 mm). Plasma concentrations of C-reactive protein, high sensitive CRP, high-density lipoproteins (HDL-c) and electronegative low density lipoproteins (LDL) were assessed in all participants. Data from medical history and socioeconomic level were also collected from patients. RESULT: Plasma levels of HDL-c were lower in subjects with periodontal disease (p = 0.016) and were inversely associated with the number of sites with PPD ≥ 3 mm (rho= -0.325) and number of sites with PPD ≥ 3 mm and CAL ≥ 3 mm (rho= -0.216). These associations remained significant after adjustments for dental plaque and smoking using Univariate Analysis of Covariance (p < 0.05). Adjusted odds ratio between periodontal disease and levels of HDL-c was 0.94 (CI95% 0.88-0.99) after adjusting for age, smoking and dental plaque. Other investigated markers of cardiovascular risk were not related to periodontal disease. CONCLUSION: Clinical parameters of periodontitis were inversely associated with plasma concentrations of HDL-c. |
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Universidade Estadual Paulista Júlio de Mesquita Filho |
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2013 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772013000500004 |
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AT dominguesjoseeduardogomes associationbetweenmarkersofcardiovascularriskandclinicalparametersofperiodontitis AT vettoremariovianna associationbetweenmarkersofcardiovascularriskandclinicalparametersofperiodontitis AT limaemersonsilva associationbetweenmarkersofcardiovascularriskandclinicalparametersofperiodontitis |
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