Do pediatric medicines induce topographic changes in dental enamel?
Abstract The purpose of the present study was to evaluate the effect of common pediatric liquid medicines on surface roughness and tooth structure loss and to evaluate the pH values of these medicines at room and cold temperatures in vitro. Eighty-four bovine enamel blocks were divided into seven groups (n = 12): G1-Alivium®, G2-Novalgina®, G3-Betamox®, G4-Clavulin®, G5-Claritin®, G6-Polaramine® and G7-Milli-Q water (negative control). The pH was determined and the samples were immersed in each treatment 3x/day for 5 min. 3D non-contact profilometry was used to determine surface roughness (linear Ra, volumetric Sa) and the Gap formed between treated and control areas in each block. Scanning electron microscopy (SEM) and energy dispersive spectrometry (EDS) were also performed. The majority of liquid medicines had pH ≤ 5.50. G1, G4, and G5 showed alterations in Ra when compared with G7 (p < 0.05). According to Sa and Gap results, only G5 was different from G7 (p < 0.05). Alteration in surface was more evident in G5 SEM images. EDS revealed high concentrations of carbon, oxygen, phosphorus, and calcium in all tested groups. Despite the low pH values of all evaluated medicines, only Alivium®, Clavulin®, and Claritin® increased linear surface roughness, and only Claritin® demonstrated the in vitro capacity to produce significant tooth structure loss.
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Sociedade Brasileira de Pesquisa Odontológica - SBPqO
2016
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oai:scielo:S1806-832420160001002112016-02-01Do pediatric medicines induce topographic changes in dental enamel?ALEXANDRIA,Adílis KalinaMECKELBURG,Nicolli de AraujoPUETTER,Ursula TavaresSALLES,Jordan TrugilhoSOUZA,Ivete Pomarico RibeiroMAIA,Lucianne Cople Dental Enamel Administration, Oral Pharmaceutical Preparations Acidity Topography Abstract The purpose of the present study was to evaluate the effect of common pediatric liquid medicines on surface roughness and tooth structure loss and to evaluate the pH values of these medicines at room and cold temperatures in vitro. Eighty-four bovine enamel blocks were divided into seven groups (n = 12): G1-Alivium®, G2-Novalgina®, G3-Betamox®, G4-Clavulin®, G5-Claritin®, G6-Polaramine® and G7-Milli-Q water (negative control). The pH was determined and the samples were immersed in each treatment 3x/day for 5 min. 3D non-contact profilometry was used to determine surface roughness (linear Ra, volumetric Sa) and the Gap formed between treated and control areas in each block. Scanning electron microscopy (SEM) and energy dispersive spectrometry (EDS) were also performed. The majority of liquid medicines had pH ≤ 5.50. G1, G4, and G5 showed alterations in Ra when compared with G7 (p < 0.05). According to Sa and Gap results, only G5 was different from G7 (p < 0.05). Alteration in surface was more evident in G5 SEM images. EDS revealed high concentrations of carbon, oxygen, phosphorus, and calcium in all tested groups. Despite the low pH values of all evaluated medicines, only Alivium®, Clavulin®, and Claritin® increased linear surface roughness, and only Claritin® demonstrated the in vitro capacity to produce significant tooth structure loss.info:eu-repo/semantics/openAccessSociedade Brasileira de Pesquisa Odontológica - SBPqOBrazilian Oral Research v.30 n.1 20162016-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242016000100211en10.1590/1807-3107BOR-2016.vol30.0011 |
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ALEXANDRIA,Adílis Kalina MECKELBURG,Nicolli de Araujo PUETTER,Ursula Tavares SALLES,Jordan Trugilho SOUZA,Ivete Pomarico Ribeiro MAIA,Lucianne Cople |
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ALEXANDRIA,Adílis Kalina MECKELBURG,Nicolli de Araujo PUETTER,Ursula Tavares SALLES,Jordan Trugilho SOUZA,Ivete Pomarico Ribeiro MAIA,Lucianne Cople Do pediatric medicines induce topographic changes in dental enamel? |
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ALEXANDRIA,Adílis Kalina MECKELBURG,Nicolli de Araujo PUETTER,Ursula Tavares SALLES,Jordan Trugilho SOUZA,Ivete Pomarico Ribeiro MAIA,Lucianne Cople |
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ALEXANDRIA,Adílis Kalina |
title |
Do pediatric medicines induce topographic changes in dental enamel? |
title_short |
Do pediatric medicines induce topographic changes in dental enamel? |
title_full |
Do pediatric medicines induce topographic changes in dental enamel? |
title_fullStr |
Do pediatric medicines induce topographic changes in dental enamel? |
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Do pediatric medicines induce topographic changes in dental enamel? |
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do pediatric medicines induce topographic changes in dental enamel? |
description |
Abstract The purpose of the present study was to evaluate the effect of common pediatric liquid medicines on surface roughness and tooth structure loss and to evaluate the pH values of these medicines at room and cold temperatures in vitro. Eighty-four bovine enamel blocks were divided into seven groups (n = 12): G1-Alivium®, G2-Novalgina®, G3-Betamox®, G4-Clavulin®, G5-Claritin®, G6-Polaramine® and G7-Milli-Q water (negative control). The pH was determined and the samples were immersed in each treatment 3x/day for 5 min. 3D non-contact profilometry was used to determine surface roughness (linear Ra, volumetric Sa) and the Gap formed between treated and control areas in each block. Scanning electron microscopy (SEM) and energy dispersive spectrometry (EDS) were also performed. The majority of liquid medicines had pH ≤ 5.50. G1, G4, and G5 showed alterations in Ra when compared with G7 (p < 0.05). According to Sa and Gap results, only G5 was different from G7 (p < 0.05). Alteration in surface was more evident in G5 SEM images. EDS revealed high concentrations of carbon, oxygen, phosphorus, and calcium in all tested groups. Despite the low pH values of all evaluated medicines, only Alivium®, Clavulin®, and Claritin® increased linear surface roughness, and only Claritin® demonstrated the in vitro capacity to produce significant tooth structure loss. |
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Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
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2016 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242016000100211 |
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