Langerhans cell histiocytosis in the maxillofacial area in adults: Report of three cases

Langerhans cell histiocytosis (LCH) is a disease of unknown etiology, characterized by proliferation of pathological Langerhans cells within different organs. It mainly affects children, but adult cases also occur, with an incidence rate of one to two per million. The head and neck are affected in almost 90% of cases. Diagnosis is made by means of histopathological analysis, and imaging studies are necessary in order to determine extent of the disease. There are no controlled trials proposing an optimal treatment protocol for LCH. Prognosis in adults is generally good due to the slow evolution of the disease and its favourable response to treatment. In our report, we present three cases of LCH in patients aged 16, 24, and 28 years respectively, with primary manifestation in the maxillofacial area. A literature review was also conducted.

Bibliographic Details

Main Authors:	García de Marcos,José Antonio, Dean Ferrer,Alicia, Alamillos Granados,Francisco, Ruiz Masera,Juan José, Barrios Sánchez,Gracia, Romero Ortiz,Ana Isabel, Calderón Bohórquez,José María, Valenzuela Salas,Borja
Format:	Digital revista
Language:	English
Published:	Sociedad Española de Medicina Oral 2007
Online Access:	http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1698-69462007000200013
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