Hip arthroplasty in HIV-infected patients

We conducted a prospective study evaluating the clinical outcome of the arthroplasty in HIV-infected patients. Between July 2000 to August 2001, 14 patients (mean age 42 years) underwent uncemented total hip replacement for osteonecrosis (10 patients) and neglected neck of femur fractures (four patients). Patients were classified according to the WHO and CDC classification and were operated by a single surgeon using the Hardinge approach. At a mean follow-up of 72 months, all patients were fully ambulant. The mean total lymphocyte count (TLC) was 2.24 cells/mm³, CD4-425 cells/mm³, CD8-873 cells/mm³ and CD4 /CD8-0.52. In three patients the CD4 counts declined to <200 and they are presently receiving antiretroviral therapy. There was no loosening, infection or dislocation. One patient sustained a periprosthetic fracture which was treated successfully non-operatively. We conclude that total hip replacement in HIV-infected patients who have not progressed to WHO stage IV can be rewarding and the procedure does not carry an increased risk of postoperative infection.

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Main Author: Brijlall,S
Format: Digital revista
Language:English
Published: Medpharm Publications 2008
Online Access:http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2008000100003
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spelling oai:scielo:S1681-150X20080001000032014-11-14Hip arthroplasty in HIV-infected patientsBrijlall,SWe conducted a prospective study evaluating the clinical outcome of the arthroplasty in HIV-infected patients. Between July 2000 to August 2001, 14 patients (mean age 42 years) underwent uncemented total hip replacement for osteonecrosis (10 patients) and neglected neck of femur fractures (four patients). Patients were classified according to the WHO and CDC classification and were operated by a single surgeon using the Hardinge approach. At a mean follow-up of 72 months, all patients were fully ambulant. The mean total lymphocyte count (TLC) was 2.24 cells/mm³, CD4-425 cells/mm³, CD8-873 cells/mm³ and CD4 /CD8-0.52. In three patients the CD4 counts declined to <200 and they are presently receiving antiretroviral therapy. There was no loosening, infection or dislocation. One patient sustained a periprosthetic fracture which was treated successfully non-operatively. We conclude that total hip replacement in HIV-infected patients who have not progressed to WHO stage IV can be rewarding and the procedure does not carry an increased risk of postoperative infection.Medpharm PublicationsSA Orthopaedic Journal v.7 n.1 20082008-03-01journal articletext/htmlhttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2008000100003en
institution SCIELO
collection OJS
country Sudáfrica
countrycode ZA
component Revista
access En linea
databasecode rev-scielo-za
tag revista
region África del Sur
libraryname SciELO
language English
format Digital
author Brijlall,S
spellingShingle Brijlall,S
Hip arthroplasty in HIV-infected patients
author_facet Brijlall,S
author_sort Brijlall,S
title Hip arthroplasty in HIV-infected patients
title_short Hip arthroplasty in HIV-infected patients
title_full Hip arthroplasty in HIV-infected patients
title_fullStr Hip arthroplasty in HIV-infected patients
title_full_unstemmed Hip arthroplasty in HIV-infected patients
title_sort hip arthroplasty in hiv-infected patients
description We conducted a prospective study evaluating the clinical outcome of the arthroplasty in HIV-infected patients. Between July 2000 to August 2001, 14 patients (mean age 42 years) underwent uncemented total hip replacement for osteonecrosis (10 patients) and neglected neck of femur fractures (four patients). Patients were classified according to the WHO and CDC classification and were operated by a single surgeon using the Hardinge approach. At a mean follow-up of 72 months, all patients were fully ambulant. The mean total lymphocyte count (TLC) was 2.24 cells/mm³, CD4-425 cells/mm³, CD8-873 cells/mm³ and CD4 /CD8-0.52. In three patients the CD4 counts declined to <200 and they are presently receiving antiretroviral therapy. There was no loosening, infection or dislocation. One patient sustained a periprosthetic fracture which was treated successfully non-operatively. We conclude that total hip replacement in HIV-infected patients who have not progressed to WHO stage IV can be rewarding and the procedure does not carry an increased risk of postoperative infection.
publisher Medpharm Publications
publishDate 2008
url http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2008000100003
work_keys_str_mv AT brijlalls hiparthroplastyinhivinfectedpatients
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