Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital
ABSTRACT Objective To describe the clinical and epidemiological features of patients with and without sepsis at critical care units of a public hospital. Methods A cross-sectional study was carried out from May 2012 to April 2013. Clinical and laboratory data of patients with and without sepsis in the intensive care units were reviewed of medical records. Results We evaluated 466 patients, 58% were men, median age was 40 years, and 146 (31%) of them were diagnosed with sepsis. The overall mortality was 20% being significantly higher for patients with sepsis (39%). The factors associated with intensive care unit mortality were the presence of sepsis (OR: 6.1, 95%CI: 3.7-10.5), age (OR: 3.6, 95%CI: 1.4-7.2), and length of hospital stay (OR: 0.96, 95%CI: 0.94-0.98). Pulmonary (49%) and intra-abdominal (20%) infections were most commonly identified sites, and coagulase-negative staphylococci and enteric Gram negative bacilli the most frequent (66%) pathogens isolated. Conclusion Although the impact of sepsis on mortality is related to patients’ clinical and epidemiological characteristics, a critical evaluation of these data is important since they will allow the direct implementation of local policies for managing this serious public health problem.
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2019
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oai:scielo:S1679-450820190002002072019-04-10Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospitalMorello,Luis GustavoDalla-Costa,Líbera MariaFontana,Rafael MialskiNetto,Ana Cristina Schmidt de OliveiraPetterle,Ricardo RasmussenConte,DanieliPereira,Luciane AparecidaKrieger,Marco AurélioRaboni,Sonia Mara Blood culture Sepsis/diagnosis Bacterial infections Critical care ABSTRACT Objective To describe the clinical and epidemiological features of patients with and without sepsis at critical care units of a public hospital. Methods A cross-sectional study was carried out from May 2012 to April 2013. Clinical and laboratory data of patients with and without sepsis in the intensive care units were reviewed of medical records. Results We evaluated 466 patients, 58% were men, median age was 40 years, and 146 (31%) of them were diagnosed with sepsis. The overall mortality was 20% being significantly higher for patients with sepsis (39%). The factors associated with intensive care unit mortality were the presence of sepsis (OR: 6.1, 95%CI: 3.7-10.5), age (OR: 3.6, 95%CI: 1.4-7.2), and length of hospital stay (OR: 0.96, 95%CI: 0.94-0.98). Pulmonary (49%) and intra-abdominal (20%) infections were most commonly identified sites, and coagulase-negative staphylococci and enteric Gram negative bacilli the most frequent (66%) pathogens isolated. Conclusion Although the impact of sepsis on mortality is related to patients’ clinical and epidemiological characteristics, a critical evaluation of these data is important since they will allow the direct implementation of local policies for managing this serious public health problem.info:eu-repo/semantics/openAccessInstituto Israelita de Ensino e Pesquisa Albert Einsteineinstein (São Paulo) v.17 n.2 20192019-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000200207en10.31744/einstein_journal/2019ao4476 |
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Morello,Luis Gustavo Dalla-Costa,Líbera Maria Fontana,Rafael Mialski Netto,Ana Cristina Schmidt de Oliveira Petterle,Ricardo Rasmussen Conte,Danieli Pereira,Luciane Aparecida Krieger,Marco Aurélio Raboni,Sonia Mara |
spellingShingle |
Morello,Luis Gustavo Dalla-Costa,Líbera Maria Fontana,Rafael Mialski Netto,Ana Cristina Schmidt de Oliveira Petterle,Ricardo Rasmussen Conte,Danieli Pereira,Luciane Aparecida Krieger,Marco Aurélio Raboni,Sonia Mara Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
author_facet |
Morello,Luis Gustavo Dalla-Costa,Líbera Maria Fontana,Rafael Mialski Netto,Ana Cristina Schmidt de Oliveira Petterle,Ricardo Rasmussen Conte,Danieli Pereira,Luciane Aparecida Krieger,Marco Aurélio Raboni,Sonia Mara |
author_sort |
Morello,Luis Gustavo |
title |
Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
title_short |
Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
title_full |
Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
title_fullStr |
Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
title_full_unstemmed |
Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
title_sort |
assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital |
description |
ABSTRACT Objective To describe the clinical and epidemiological features of patients with and without sepsis at critical care units of a public hospital. Methods A cross-sectional study was carried out from May 2012 to April 2013. Clinical and laboratory data of patients with and without sepsis in the intensive care units were reviewed of medical records. Results We evaluated 466 patients, 58% were men, median age was 40 years, and 146 (31%) of them were diagnosed with sepsis. The overall mortality was 20% being significantly higher for patients with sepsis (39%). The factors associated with intensive care unit mortality were the presence of sepsis (OR: 6.1, 95%CI: 3.7-10.5), age (OR: 3.6, 95%CI: 1.4-7.2), and length of hospital stay (OR: 0.96, 95%CI: 0.94-0.98). Pulmonary (49%) and intra-abdominal (20%) infections were most commonly identified sites, and coagulase-negative staphylococci and enteric Gram negative bacilli the most frequent (66%) pathogens isolated. Conclusion Although the impact of sepsis on mortality is related to patients’ clinical and epidemiological characteristics, a critical evaluation of these data is important since they will allow the direct implementation of local policies for managing this serious public health problem. |
publisher |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publishDate |
2019 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000200207 |
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