Is male infertility a forerunner to cancer?

Is male infertility a forerunner to cancer?

PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.

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Main Authors: Burns,Whitney R., Sabanegh,Edmund, Dada,Rima, Rein,Brandon, Agarwal,Ashok
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Urologia 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002
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spelling oai:scielo:S1677-553820100005000022010-12-06Is male infertility a forerunner to cancer?Burns,Whitney R.Sabanegh,EdmundDada,RimaRein,BrandonAgarwal,Ashok male infertility endocrine-disruption testicular cancer testicular dysgenesis PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.info:eu-repo/semantics/openAccessSociedade Brasileira de UrologiaInternational braz j urol v.36 n.5 20102010-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002en10.1590/S1677-55382010000500002
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countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Burns,Whitney R.
Sabanegh,Edmund
Dada,Rima
Rein,Brandon
Agarwal,Ashok
spellingShingle Burns,Whitney R.
Sabanegh,Edmund
Dada,Rima
Rein,Brandon
Agarwal,Ashok
Is male infertility a forerunner to cancer?
author_facet Burns,Whitney R.
Sabanegh,Edmund
Dada,Rima
Rein,Brandon
Agarwal,Ashok
author_sort Burns,Whitney R.
title Is male infertility a forerunner to cancer?
title_short Is male infertility a forerunner to cancer?
title_full Is male infertility a forerunner to cancer?
title_fullStr Is male infertility a forerunner to cancer?
title_full_unstemmed Is male infertility a forerunner to cancer?
title_sort is male infertility a forerunner to cancer?
description PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.
publisher Sociedade Brasileira de Urologia
publishDate 2010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002
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AT sabaneghedmund ismaleinfertilityaforerunnertocancer
AT dadarima ismaleinfertilityaforerunnertocancer
AT reinbrandon ismaleinfertilityaforerunnertocancer
AT agarwalashok ismaleinfertilityaforerunnertocancer
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