Leiomyosarcoma of the great saphenous vein

A 56-year-old male patient presented with a complaint of two painful, hard, palpable nodules in the right lower limb. A Doppler ultrasound scan revealed the presence of nodules, likely to be neoplastic. Computed angiography showed two solid hypervascular nodules in the right great saphenous vein, fed by branches of the posterior tibial artery. Embolization of the nodules using surgical cyanoacrylate was performed, followed by an excisional biopsy. Anatomical pathology and immunohistochemical analysis identified the nodule as a high-grade leiomyosarcoma, characterized by ten mitotic figures per ten high-power fields, necrosis and cell pleomorphism. Immunohistochemical analysis results were positive for caldesmon and desmin labeling. A second surgical procedure was performed to enlarge the free margins.

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Main Authors: Amato,Alexandre Campos Moraes, Silva,Ana Júlia de Deus, Santos,Ricardo Virgínio dos, Amato,Salvador José de Toledo Arruda
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492015000200186
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spelling oai:scielo:S1677-544920150002001862015-08-20Leiomyosarcoma of the great saphenous veinAmato,Alexandre Campos MoraesSilva,Ana Júlia de DeusSantos,Ricardo Virgínio dosAmato,Salvador José de Toledo Arruda neoplasms vascular tissue neoplasms blood vessels A 56-year-old male patient presented with a complaint of two painful, hard, palpable nodules in the right lower limb. A Doppler ultrasound scan revealed the presence of nodules, likely to be neoplastic. Computed angiography showed two solid hypervascular nodules in the right great saphenous vein, fed by branches of the posterior tibial artery. Embolization of the nodules using surgical cyanoacrylate was performed, followed by an excisional biopsy. Anatomical pathology and immunohistochemical analysis identified the nodule as a high-grade leiomyosarcoma, characterized by ten mitotic figures per ten high-power fields, necrosis and cell pleomorphism. Immunohistochemical analysis results were positive for caldesmon and desmin labeling. A second surgical procedure was performed to enlarge the free margins.info:eu-repo/semantics/openAccessSociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)Jornal Vascular Brasileiro v.14 n.2 20152015-06-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492015000200186en10.1590/1677-5449.0077
institution SCIELO
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country Brasil
countrycode BR
component Revista
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Amato,Alexandre Campos Moraes
Silva,Ana Júlia de Deus
Santos,Ricardo Virgínio dos
Amato,Salvador José de Toledo Arruda
spellingShingle Amato,Alexandre Campos Moraes
Silva,Ana Júlia de Deus
Santos,Ricardo Virgínio dos
Amato,Salvador José de Toledo Arruda
Leiomyosarcoma of the great saphenous vein
author_facet Amato,Alexandre Campos Moraes
Silva,Ana Júlia de Deus
Santos,Ricardo Virgínio dos
Amato,Salvador José de Toledo Arruda
author_sort Amato,Alexandre Campos Moraes
title Leiomyosarcoma of the great saphenous vein
title_short Leiomyosarcoma of the great saphenous vein
title_full Leiomyosarcoma of the great saphenous vein
title_fullStr Leiomyosarcoma of the great saphenous vein
title_full_unstemmed Leiomyosarcoma of the great saphenous vein
title_sort leiomyosarcoma of the great saphenous vein
description A 56-year-old male patient presented with a complaint of two painful, hard, palpable nodules in the right lower limb. A Doppler ultrasound scan revealed the presence of nodules, likely to be neoplastic. Computed angiography showed two solid hypervascular nodules in the right great saphenous vein, fed by branches of the posterior tibial artery. Embolization of the nodules using surgical cyanoacrylate was performed, followed by an excisional biopsy. Anatomical pathology and immunohistochemical analysis identified the nodule as a high-grade leiomyosarcoma, characterized by ten mitotic figures per ten high-power fields, necrosis and cell pleomorphism. Immunohistochemical analysis results were positive for caldesmon and desmin labeling. A second surgical procedure was performed to enlarge the free margins.
publisher Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492015000200186
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AT silvaanajuliadedeus leiomyosarcomaofthegreatsaphenousvein
AT santosricardovirginiodos leiomyosarcomaofthegreatsaphenousvein
AT amatosalvadorjosedetoledoarruda leiomyosarcomaofthegreatsaphenousvein
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