Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix
ABSTRACT Monilethrix is a genetic condition that affects the hair shaft. We describe a family with this disease, focusing on its clinical aspects and microscopic hair characteristics. The patient was a 10-year-old female with history of hypotrichosis. In addition to diffuse alopecia, there was brittle hair, with ruptures in the hair shaft at different levels. The hair had a nodular appearance at naked eye. Other family members had the same symptoms, what indicates an autosomal dominant pattern of inheritance. Microscopic analysis revealed capillary fibers with areas of elliptical nodular appearance interspersed with regions of dystrophic constriction.
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Sociedade Brasileira de Patologia Clínica
2018
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oai:scielo:S1676-244420180005003332018-12-03Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrixFerreira,Maria Angélica T.Gonzales,João Francisco O.Diniz,Bruna L.Floriani,Maiara A.Bau,Ana Elisa K.Rosa,Rosana C. M.Rosa,Rafael Fabiano M.Zen,Paulo Ricardo G. monilethrix hair hypotrichosis inheritance patterns microscopy ABSTRACT Monilethrix is a genetic condition that affects the hair shaft. We describe a family with this disease, focusing on its clinical aspects and microscopic hair characteristics. The patient was a 10-year-old female with history of hypotrichosis. In addition to diffuse alopecia, there was brittle hair, with ruptures in the hair shaft at different levels. The hair had a nodular appearance at naked eye. Other family members had the same symptoms, what indicates an autosomal dominant pattern of inheritance. Microscopic analysis revealed capillary fibers with areas of elliptical nodular appearance interspersed with regions of dystrophic constriction.info:eu-repo/semantics/openAccessSociedade Brasileira de Patologia Clínica Jornal Brasileiro de Patologia e Medicina Laboratorial v.54 n.5 20182018-10-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442018000500333en10.5935/1676-2444.20180055 |
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Ferreira,Maria Angélica T. Gonzales,João Francisco O. Diniz,Bruna L. Floriani,Maiara A. Bau,Ana Elisa K. Rosa,Rosana C. M. Rosa,Rafael Fabiano M. Zen,Paulo Ricardo G. |
| spellingShingle |
Ferreira,Maria Angélica T. Gonzales,João Francisco O. Diniz,Bruna L. Floriani,Maiara A. Bau,Ana Elisa K. Rosa,Rosana C. M. Rosa,Rafael Fabiano M. Zen,Paulo Ricardo G. Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| author_facet |
Ferreira,Maria Angélica T. Gonzales,João Francisco O. Diniz,Bruna L. Floriani,Maiara A. Bau,Ana Elisa K. Rosa,Rosana C. M. Rosa,Rafael Fabiano M. Zen,Paulo Ricardo G. |
| author_sort |
Ferreira,Maria Angélica T. |
| title |
Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| title_short |
Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| title_full |
Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| title_fullStr |
Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| title_full_unstemmed |
Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| title_sort |
description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix |
| description |
ABSTRACT Monilethrix is a genetic condition that affects the hair shaft. We describe a family with this disease, focusing on its clinical aspects and microscopic hair characteristics. The patient was a 10-year-old female with history of hypotrichosis. In addition to diffuse alopecia, there was brittle hair, with ruptures in the hair shaft at different levels. The hair had a nodular appearance at naked eye. Other family members had the same symptoms, what indicates an autosomal dominant pattern of inheritance. Microscopic analysis revealed capillary fibers with areas of elliptical nodular appearance interspersed with regions of dystrophic constriction. |
| publisher |
Sociedade Brasileira de Patologia Clínica |
| publishDate |
2018 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442018000500333 |
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