Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices

ABSTRACT Introduction: Elevated plasma levels of lipids are considered the main modifiable risk factor for the cardiovascular disease. The Point-of-care testing (POCT) method provides quick results and allows anticipating diagnosis and treatment. Objective: To compare the lipid profile results obtained from both POCT and the traditional clinical laboratory. Methods: Fasting blood samples were collected from 111 patients who sought, for any reason, the private medical offices participating on this study. Capillary whole blood samples were analyzed in CardioChek® PA (CCPA) equipment, and the serum samples were analyzed in clinical laboratories (LAB) that have internal and external quality control, with certification. The mean values of each variable of the lipid profile obtained by CCPA and LAB were calculated. Linear regression was used to determine the existence of correlation between the two methods. Results: We observed a positive correlation between the values obtained by CCPA and LAB for all variables of the lipid profile. Our data, extracted from the routine use of CCPA in private medical offices, supports a substantial contribution of the POCT methodology in the detection of the main cardiovascular risk factors. Conclusion: The POCT CardioChek® PA Analyzer is an easy-to-operate tool, with adequate analytical performance and a good correlation with the results of the conventional laboratory method, therefore, considered a reliable method.

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Main Authors: Xavier,Hermes T., Ruiz,Rogerio M., Kencis Jr.,Luiz, Melone,Giovanni, Costa,William, Fraga,Raffael Francisco, Wajman,Luciano, Krakauer,Marcio, Scartezini,Marileia
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000600387
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spelling oai:scielo:S1676-244420160006003872017-01-10Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical officesXavier,Hermes T.Ruiz,Rogerio M.Kencis Jr.,LuizMelone,GiovanniCosta,WilliamFraga,Raffael FranciscoWajman,LucianoKrakauer,MarcioScartezini,Marileia lipids point-of-care testing cardiovascular diseases ABSTRACT Introduction: Elevated plasma levels of lipids are considered the main modifiable risk factor for the cardiovascular disease. The Point-of-care testing (POCT) method provides quick results and allows anticipating diagnosis and treatment. Objective: To compare the lipid profile results obtained from both POCT and the traditional clinical laboratory. Methods: Fasting blood samples were collected from 111 patients who sought, for any reason, the private medical offices participating on this study. Capillary whole blood samples were analyzed in CardioChek® PA (CCPA) equipment, and the serum samples were analyzed in clinical laboratories (LAB) that have internal and external quality control, with certification. The mean values of each variable of the lipid profile obtained by CCPA and LAB were calculated. Linear regression was used to determine the existence of correlation between the two methods. Results: We observed a positive correlation between the values obtained by CCPA and LAB for all variables of the lipid profile. Our data, extracted from the routine use of CCPA in private medical offices, supports a substantial contribution of the POCT methodology in the detection of the main cardiovascular risk factors. Conclusion: The POCT CardioChek® PA Analyzer is an easy-to-operate tool, with adequate analytical performance and a good correlation with the results of the conventional laboratory method, therefore, considered a reliable method.info:eu-repo/semantics/openAccessSociedade Brasileira de Patologia Clínica Jornal Brasileiro de Patologia e Medicina Laboratorial v.52 n.6 20162016-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000600387en10.5935/1676-2444.20160057
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libraryname SciELO
language English
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author Xavier,Hermes T.
Ruiz,Rogerio M.
Kencis Jr.,Luiz
Melone,Giovanni
Costa,William
Fraga,Raffael Francisco
Wajman,Luciano
Krakauer,Marcio
Scartezini,Marileia
spellingShingle Xavier,Hermes T.
Ruiz,Rogerio M.
Kencis Jr.,Luiz
Melone,Giovanni
Costa,William
Fraga,Raffael Francisco
Wajman,Luciano
Krakauer,Marcio
Scartezini,Marileia
Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
author_facet Xavier,Hermes T.
Ruiz,Rogerio M.
Kencis Jr.,Luiz
Melone,Giovanni
Costa,William
Fraga,Raffael Francisco
Wajman,Luciano
Krakauer,Marcio
Scartezini,Marileia
author_sort Xavier,Hermes T.
title Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
title_short Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
title_full Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
title_fullStr Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
title_full_unstemmed Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
title_sort clinical correlation between the point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices
description ABSTRACT Introduction: Elevated plasma levels of lipids are considered the main modifiable risk factor for the cardiovascular disease. The Point-of-care testing (POCT) method provides quick results and allows anticipating diagnosis and treatment. Objective: To compare the lipid profile results obtained from both POCT and the traditional clinical laboratory. Methods: Fasting blood samples were collected from 111 patients who sought, for any reason, the private medical offices participating on this study. Capillary whole blood samples were analyzed in CardioChek® PA (CCPA) equipment, and the serum samples were analyzed in clinical laboratories (LAB) that have internal and external quality control, with certification. The mean values of each variable of the lipid profile obtained by CCPA and LAB were calculated. Linear regression was used to determine the existence of correlation between the two methods. Results: We observed a positive correlation between the values obtained by CCPA and LAB for all variables of the lipid profile. Our data, extracted from the routine use of CCPA in private medical offices, supports a substantial contribution of the POCT methodology in the detection of the main cardiovascular risk factors. Conclusion: The POCT CardioChek® PA Analyzer is an easy-to-operate tool, with adequate analytical performance and a good correlation with the results of the conventional laboratory method, therefore, considered a reliable method.
publisher Sociedade Brasileira de Patologia Clínica
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000600387
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