Inclusion-body myositis: a difficult diagnosis?
Sporadic inclusion-body myositis (IBM) is the most common myopathy in individuals over 55 years of age. However, in many cases, the diagnosis is neglected. Its main findings include progressive muscle weakness, normal or low levels of serum creatine kinase, and the absence of a response to immunosuppression. Muscle biopsy shows inflammatory reaction in association with degenerative changes of the muscle fibers. We report a typical case of IBM, in which diagnosis was possible only after three muscle biopsies. The challenges to confirm histological diagnosis and the caution to avoid repeating tests are discussed.
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Main Authors: | Correia,Carolina da Cunha, Magalhães,Maria Clara de Oliveira, Barbosa,Pedro Lucas de Mendonça, Campos,Eliene Dutra, Zanoteli,Edmar |
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Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Patologia Clínica
2014
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442014000500364 |
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