Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report
Adenomyoepitheliomas (AMEs) are rare breast lesions, which are characterized by the proliferation of epithelial and myoepithelial cells. They are circumscribed lesions, which can be clinically and mammographically detected. However, when they are indistinctly limited, differential diagnosis with malignant lesions becomes difficult. In this paper, we report a case of adenomyoepithelioma with malignant transformation of the myoepithelial component, a rare histological type that arises from the malignant transformation of epithelial, myoepithelial, or both elements. Its course and prognosis are uncertain. Mastectomy with sentinel lymph node biopsy followed by radiotherapy are the most effective treatment approaches.
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Sociedade Brasileira de Patologia Clínica
2011
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oai:scielo:S1676-244420110005000072011-11-08Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case reportRossetti,ClaudiaAzzalis,Ligia AjaimeJunqueira,Virginia Berlanga CamposGuidoni,Regina MariaGomes,Mara Regina AlcaláFonseca,Fernando Luiz Affonso Adenomyoepithelioma Breast Carcinoma Malignant Adenomyoepitheliomas (AMEs) are rare breast lesions, which are characterized by the proliferation of epithelial and myoepithelial cells. They are circumscribed lesions, which can be clinically and mammographically detected. However, when they are indistinctly limited, differential diagnosis with malignant lesions becomes difficult. In this paper, we report a case of adenomyoepithelioma with malignant transformation of the myoepithelial component, a rare histological type that arises from the malignant transformation of epithelial, myoepithelial, or both elements. Its course and prognosis are uncertain. Mastectomy with sentinel lymph node biopsy followed by radiotherapy are the most effective treatment approaches.info:eu-repo/semantics/openAccessSociedade Brasileira de Patologia Clínica Jornal Brasileiro de Patologia e Medicina Laboratorial v.47 n.5 20112011-10-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442011000500007en10.1590/S1676-24442011000500007 |
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Rossetti,Claudia Azzalis,Ligia Ajaime Junqueira,Virginia Berlanga Campos Guidoni,Regina Maria Gomes,Mara Regina Alcalá Fonseca,Fernando Luiz Affonso |
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Rossetti,Claudia Azzalis,Ligia Ajaime Junqueira,Virginia Berlanga Campos Guidoni,Regina Maria Gomes,Mara Regina Alcalá Fonseca,Fernando Luiz Affonso Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| author_facet |
Rossetti,Claudia Azzalis,Ligia Ajaime Junqueira,Virginia Berlanga Campos Guidoni,Regina Maria Gomes,Mara Regina Alcalá Fonseca,Fernando Luiz Affonso |
| author_sort |
Rossetti,Claudia |
| title |
Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| title_short |
Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| title_full |
Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| title_fullStr |
Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| title_full_unstemmed |
Adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| title_sort |
adenomyoepithelioma with malignant transformation diagnosed by immunohistochemical analysis: case report |
| description |
Adenomyoepitheliomas (AMEs) are rare breast lesions, which are characterized by the proliferation of epithelial and myoepithelial cells. They are circumscribed lesions, which can be clinically and mammographically detected. However, when they are indistinctly limited, differential diagnosis with malignant lesions becomes difficult. In this paper, we report a case of adenomyoepithelioma with malignant transformation of the myoepithelial component, a rare histological type that arises from the malignant transformation of epithelial, myoepithelial, or both elements. Its course and prognosis are uncertain. Mastectomy with sentinel lymph node biopsy followed by radiotherapy are the most effective treatment approaches. |
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Sociedade Brasileira de Patologia Clínica |
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2011 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442011000500007 |
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| _version_ |
1756427477928902656 |