COVID-19 pandemic: challenges ahead

Abstract Since December 2019, health systems worldwide have faced the pandemic caused by the new severe acute respiratory syndrome coronavirus 2. The pandemic began in China and has spread throughout the world. This new coronavirus has a high transmission capacity and elevated lethality in people over 60 years old and in those with risk factors (obesity, diabetes, and systemic arterial hypertension); those characteristics have a different proportion in each country. At present, there is no specific, effective, and safe treatment to treat this virus. In this review, an analysis is made on the differences in epidemiological aspects of the disease and its presentation in pediatric patients; the poorly-based recommendation for using an empirical combination of antimalarials plus antimicrobials as antiviral treatment; the indication of intravenous steroids; and the possible influence of antihypertensive drugs on the course of the disease.

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Main Authors: Márquez-González,Horacio, Miranda-Novales,María G., Solórzano-Santos,Fortino, Klunder-Klunder,Miguel, Garduño-Espinoza,Juan, Méndez-Galván,Jorge F.
Format: Digital revista
Language:English
Published: Instituto Nacional de Salud, Hospital Infantil de México Federico Gómez 2020
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-11462020000500242
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spelling oai:scielo:S1665-114620200005002422020-11-10COVID-19 pandemic: challenges aheadMárquez-González,HoracioMiranda-Novales,María G.Solórzano-Santos,FortinoKlunder-Klunder,MiguelGarduño-Espinoza,JuanMéndez-Galván,Jorge F. Coronavirus 2019 disease Severe acute respiratory syndrome coronavirus 2 Hydroxychloroquine Azithromycin Steroids Angiotensin-converting enzyme-2 Abstract Since December 2019, health systems worldwide have faced the pandemic caused by the new severe acute respiratory syndrome coronavirus 2. The pandemic began in China and has spread throughout the world. This new coronavirus has a high transmission capacity and elevated lethality in people over 60 years old and in those with risk factors (obesity, diabetes, and systemic arterial hypertension); those characteristics have a different proportion in each country. At present, there is no specific, effective, and safe treatment to treat this virus. In this review, an analysis is made on the differences in epidemiological aspects of the disease and its presentation in pediatric patients; the poorly-based recommendation for using an empirical combination of antimalarials plus antimicrobials as antiviral treatment; the indication of intravenous steroids; and the possible influence of antihypertensive drugs on the course of the disease.info:eu-repo/semantics/openAccessInstituto Nacional de Salud, Hospital Infantil de México Federico GómezBoletín médico del Hospital Infantil de México v.77 n.5 20202020-10-01info:eu-repo/semantics/articletext/htmlhttp://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-11462020000500242en10.24875/bmhim.20000166
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language English
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author Márquez-González,Horacio
Miranda-Novales,María G.
Solórzano-Santos,Fortino
Klunder-Klunder,Miguel
Garduño-Espinoza,Juan
Méndez-Galván,Jorge F.
spellingShingle Márquez-González,Horacio
Miranda-Novales,María G.
Solórzano-Santos,Fortino
Klunder-Klunder,Miguel
Garduño-Espinoza,Juan
Méndez-Galván,Jorge F.
COVID-19 pandemic: challenges ahead
author_facet Márquez-González,Horacio
Miranda-Novales,María G.
Solórzano-Santos,Fortino
Klunder-Klunder,Miguel
Garduño-Espinoza,Juan
Méndez-Galván,Jorge F.
author_sort Márquez-González,Horacio
title COVID-19 pandemic: challenges ahead
title_short COVID-19 pandemic: challenges ahead
title_full COVID-19 pandemic: challenges ahead
title_fullStr COVID-19 pandemic: challenges ahead
title_full_unstemmed COVID-19 pandemic: challenges ahead
title_sort covid-19 pandemic: challenges ahead
description Abstract Since December 2019, health systems worldwide have faced the pandemic caused by the new severe acute respiratory syndrome coronavirus 2. The pandemic began in China and has spread throughout the world. This new coronavirus has a high transmission capacity and elevated lethality in people over 60 years old and in those with risk factors (obesity, diabetes, and systemic arterial hypertension); those characteristics have a different proportion in each country. At present, there is no specific, effective, and safe treatment to treat this virus. In this review, an analysis is made on the differences in epidemiological aspects of the disease and its presentation in pediatric patients; the poorly-based recommendation for using an empirical combination of antimalarials plus antimicrobials as antiviral treatment; the indication of intravenous steroids; and the possible influence of antihypertensive drugs on the course of the disease.
publisher Instituto Nacional de Salud, Hospital Infantil de México Federico Gómez
publishDate 2020
url http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-11462020000500242
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AT klunderklundermiguel covid19pandemicchallengesahead
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