Follicle-stimulating-hormone-secreting pituitary macroadenoma: a challenging diagnosis in gynecology

Abstract Menstrual irregularities account for up to 30% of outpatient visits to gynecologists. We present a case of a 29-year-old nulliparous woman with abnormal vaginal bleeding for the last five years. A transvaginal ultrasound revealed both ovaries enlarged with multiple cysts. Blood tests showed mildly elevated levels of estradiol and prolactin, and a suppressed LH. Cerebral MRI showed a pituitary macroadenoma. The patient was submitted to transsphenoidal surgery. The final diagnosis was pituitary adenoma with FSH and LH expression. Cases of pituitary adenomas causing clinical symptoms are unusual This diagnosis should be considered in women with menstrual irregularities and hyperstimulated ovaries.

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Bibliographic Details
Main Authors: Peixinho,Catarina, Neves,João Pedro, Canão,Pedro, Bem,Pedro, Fortuna,João
Format: Digital revista
Language:English
Published: Euromédice, Edições Médicas Lda. 2020
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302020000400257
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