Hancornia speciosa serum latex fraction: a non-allergenic biomaterial
Abstract Plant-derived products can assist in the healing process of dermal wounds. It has been demonstrated that Hancornia speciosa latex present angiogenic, osteogenic, anti-inflammatory, and antioxidant activities. Then, it could contribute to the wound healing process. However, natural products in contact with skin may cause dermatitis. The objective of this work was to evaluate the allergic and irritant potential of H. speciosa serum fraction latex using in vitro assays. The obtained results showed that the H. speciosa serum fraction latex has a slightly irritant potential and is not cytotoxic neither allergenic for human cells. Moreover, we identified a remarkable low amount of proteins in this material in comparison to Hevea brasiliensis latex. This result could explain the non-allergenic potential of H. speciosa serum fraction latex because proteins present in latex are the main responsible for allergy. This biomaterial could be used as a non-allergenic source for development of new medicines.
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Instituto Internacional de Ecologia
2023
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oai:scielo:S1519-698420230001002752021-10-07Hancornia speciosa serum latex fraction: a non-allergenic biomaterialCosta,A. F.Gonçalves,K. C.Bailão,E. F. L. C.Caramori,S. S.Valadares,M. C.Gonçalves,P. J.Almeida,L. M. allergic contact dermatitis chronic wounds irritant contact dermatitis mangabeira wound healing Abstract Plant-derived products can assist in the healing process of dermal wounds. It has been demonstrated that Hancornia speciosa latex present angiogenic, osteogenic, anti-inflammatory, and antioxidant activities. Then, it could contribute to the wound healing process. However, natural products in contact with skin may cause dermatitis. The objective of this work was to evaluate the allergic and irritant potential of H. speciosa serum fraction latex using in vitro assays. The obtained results showed that the H. speciosa serum fraction latex has a slightly irritant potential and is not cytotoxic neither allergenic for human cells. Moreover, we identified a remarkable low amount of proteins in this material in comparison to Hevea brasiliensis latex. This result could explain the non-allergenic potential of H. speciosa serum fraction latex because proteins present in latex are the main responsible for allergy. This biomaterial could be used as a non-allergenic source for development of new medicines.info:eu-repo/semantics/openAccessInstituto Internacional de EcologiaBrazilian Journal of Biology v.83 20232023-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100275en10.1590/1519-6984.251075 |
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Costa,A. F. Gonçalves,K. C. Bailão,E. F. L. C. Caramori,S. S. Valadares,M. C. Gonçalves,P. J. Almeida,L. M. |
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Costa,A. F. Gonçalves,K. C. Bailão,E. F. L. C. Caramori,S. S. Valadares,M. C. Gonçalves,P. J. Almeida,L. M. Hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
author_facet |
Costa,A. F. Gonçalves,K. C. Bailão,E. F. L. C. Caramori,S. S. Valadares,M. C. Gonçalves,P. J. Almeida,L. M. |
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Costa,A. F. |
title |
Hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
title_short |
Hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
title_full |
Hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
title_fullStr |
Hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
title_full_unstemmed |
Hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
title_sort |
hancornia speciosa serum latex fraction: a non-allergenic biomaterial |
description |
Abstract Plant-derived products can assist in the healing process of dermal wounds. It has been demonstrated that Hancornia speciosa latex present angiogenic, osteogenic, anti-inflammatory, and antioxidant activities. Then, it could contribute to the wound healing process. However, natural products in contact with skin may cause dermatitis. The objective of this work was to evaluate the allergic and irritant potential of H. speciosa serum fraction latex using in vitro assays. The obtained results showed that the H. speciosa serum fraction latex has a slightly irritant potential and is not cytotoxic neither allergenic for human cells. Moreover, we identified a remarkable low amount of proteins in this material in comparison to Hevea brasiliensis latex. This result could explain the non-allergenic potential of H. speciosa serum fraction latex because proteins present in latex are the main responsible for allergy. This biomaterial could be used as a non-allergenic source for development of new medicines. |
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Instituto Internacional de Ecologia |
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2023 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100275 |
work_keys_str_mv |
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