Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans

Abstract In the present work, twelve bacilli were isolated from four different regions of human skin from Bela population of Nagpur district, India. The isolated bacilli were identified by their morphological, cultural and biochemical characteristics. Seven isolates were Gram negative rods, out of which five were belong to genus Pseudomonas. Three among the five Gram positive isolates were identified as Dermabactor and the remaining two Bacillus. Their antimicrobial susceptibility profile was determined by Kirby-Bauer disc diffusion method. The isolates showed resistance to several currently used broad-spectrum antibiotics. The Dermabactor genus was resistant to vancomycin, although it was earlier reported to be susceptible. Imipenem was found to be the most effective antibiotic for Pseudomonas while nalidixic acid, ampicillin and tetracycline were ineffective. Isolates of Bacillus displayed resistance to the extended spectrum antibiotics cephalosporin and ceftazidime. Imipenem, carbenicillin and ticarcillin were found to be the most effective antibiotics as all the investigated isolates were susceptible to them. Antibiotic resistance may be due to the overuse or misuse of antibiotics during the treatment, or following constant exposure to antibiotic-containing cosmetic formulations.

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Main Authors: Tarale,Prashant, Gawande,Sonali, Jambhulkar,Vinay
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Microbiologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401111
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spelling oai:scielo:S1517-838220150004011112015-12-17Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humansTarale,PrashantGawande,SonaliJambhulkar,Vinay antibiotic resistance identification microflora nosocomial opportunistic Abstract In the present work, twelve bacilli were isolated from four different regions of human skin from Bela population of Nagpur district, India. The isolated bacilli were identified by their morphological, cultural and biochemical characteristics. Seven isolates were Gram negative rods, out of which five were belong to genus Pseudomonas. Three among the five Gram positive isolates were identified as Dermabactor and the remaining two Bacillus. Their antimicrobial susceptibility profile was determined by Kirby-Bauer disc diffusion method. The isolates showed resistance to several currently used broad-spectrum antibiotics. The Dermabactor genus was resistant to vancomycin, although it was earlier reported to be susceptible. Imipenem was found to be the most effective antibiotic for Pseudomonas while nalidixic acid, ampicillin and tetracycline were ineffective. Isolates of Bacillus displayed resistance to the extended spectrum antibiotics cephalosporin and ceftazidime. Imipenem, carbenicillin and ticarcillin were found to be the most effective antibiotics as all the investigated isolates were susceptible to them. Antibiotic resistance may be due to the overuse or misuse of antibiotics during the treatment, or following constant exposure to antibiotic-containing cosmetic formulations.info:eu-repo/semantics/openAccessSociedade Brasileira de MicrobiologiaBrazilian Journal of Microbiology v.46 n.4 20152015-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401111en10.1590/S1517-838246420131366
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Tarale,Prashant
Gawande,Sonali
Jambhulkar,Vinay
spellingShingle Tarale,Prashant
Gawande,Sonali
Jambhulkar,Vinay
Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
author_facet Tarale,Prashant
Gawande,Sonali
Jambhulkar,Vinay
author_sort Tarale,Prashant
title Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
title_short Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
title_full Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
title_fullStr Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
title_full_unstemmed Antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
title_sort antibiotic susceptibility profile of bacilli isolated from the skin of healthy humans
description Abstract In the present work, twelve bacilli were isolated from four different regions of human skin from Bela population of Nagpur district, India. The isolated bacilli were identified by their morphological, cultural and biochemical characteristics. Seven isolates were Gram negative rods, out of which five were belong to genus Pseudomonas. Three among the five Gram positive isolates were identified as Dermabactor and the remaining two Bacillus. Their antimicrobial susceptibility profile was determined by Kirby-Bauer disc diffusion method. The isolates showed resistance to several currently used broad-spectrum antibiotics. The Dermabactor genus was resistant to vancomycin, although it was earlier reported to be susceptible. Imipenem was found to be the most effective antibiotic for Pseudomonas while nalidixic acid, ampicillin and tetracycline were ineffective. Isolates of Bacillus displayed resistance to the extended spectrum antibiotics cephalosporin and ceftazidime. Imipenem, carbenicillin and ticarcillin were found to be the most effective antibiotics as all the investigated isolates were susceptible to them. Antibiotic resistance may be due to the overuse or misuse of antibiotics during the treatment, or following constant exposure to antibiotic-containing cosmetic formulations.
publisher Sociedade Brasileira de Microbiologia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401111
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