A modified pH-cycling model to evaluate fluoride effect on enamel demineralization
Since in vitro pH-cycling models are widely used to study dental caries, they should allow evaluations of fluoride effect on early stages of caries development. Therefore, acid etching on enamel surface must be avoided, enabling surface microhardness (SMH) analysis. In the present study, the pH-cycling model originally described by Featherstone et al.9 (1986) was modified to preserve the enamel surface and to produce early carious lesions that could be evaluated using SMH and cross-sectional microhardness (CSMH) measurements. In order to validate this modified model, a dose-response evaluation with fluoride was made. Human enamel blocks with known SMH were submitted to such regimen with the following treatments: distilled deionized water (DDW; control) and solutions containing 70, 140 and 280 ppm F. Data from %SMH change and deltaZ (mineral loss) showed a statistically significant negative correlation between F concentration in treatment solutions and mineral loss. In conclusion, the modified pH-cycling model allowed the evaluation of changes on the outermost enamel layer during caries development, and a dose-response effect of fluoride reducing enamel demineralization was observed.
Main Authors: | Argenta,Rosane Maria Orth, Tabchoury,Cinthia Pereira Machado, Cury,Jaime Aparecido |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Pesquisa Odontológica e Faculdade de Odontologia da Universidade de São Paulo
2003
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-74912003000300008 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Fluoride bioavailability on demineralized enamel by commercial mouthrinses
by: Valdivia-Tapia,Astrid Carolina, et al.
Published: (2021) -
Effect of fluoridated varnish and silver diamine fluoride solution on enamel demineralization: pH-cycling study
by: Delbem,Alberto Carlos Botazzo, et al.
Published: (2006) -
Effect of Fluoride Concentration on Reduction of Enamel Demineralization According to the Cariogenic Challenge
by: Noronha,Mayara dos Santos, et al.
Published: (2016) -
Fluoride bioavailability on demineralized enamel by commercial mouth rinses
by: Valdivia-Tapia,Astrid Carolina, et al.
Published: (2021) -
Evaluation of commercial fluoride solutions on bovine enamel demineralization, using pH-cycling model
by: Carvalho,Maira de Souza, et al.
Published: (2010)