Evaluation of different media for the production of cephalosporins by Streptomyces clavuligerus ATCC 27064
The aim of this work was to compare the composition of a complex and soluble culture medium to eight other media described in the literature through the batch cultivation in a conventional bench-scale bioreactor for the production of cephamycin C by a wild strain of Streptomyces clavuligerus. The proposed medium resulted in an antibiotic production 1.5 to 7.5 times higher than the other culture media.
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Main Authors: | Antonio,Tatiana, Bellão,Carolina, Corrêa,Tatiana, Cavallieri,André Pastrelo, Badino,Alberto Colli, Araujo,Maria Lucia Gonsales da Costa |
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Format: | Digital revista |
Language: | English |
Published: |
Instituto de Tecnologia do Paraná - Tecpar
2012
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000600003 |
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