Liquid kit for preparation of 188rhenium-etidronate

The aim of this study was the preparation of a liquid kit for radiolabeling of 188Re-HEDP (hydroxyethylidene diphosphonate). 188Re was obtained from alumina based 188W/188Re generators. This paper reports the efficacy of a cold kit stored for more than two weeks, determined by the dependence of the radiolabeling yields of 188Re-HEDP on the incubation time, reducing agent concentration, the effects of concentration of ligand, the pH of the reaction and the temperature. The cold kits showed a good stability when carrie-free rhenium-188 was added in the reaction mixture.

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Bibliographic Details
Main Authors: Marczewski,Barbara, Dias,Carla Roberta, Moraes,Vanessa, Osso Junior,João Alberto
Format: Digital revista
Language:English
Published: Instituto de Tecnologia do Paraná - Tecpar 2005
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700019
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