Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines

Long-term selection experiments provide a valuable resource for understanding the genetic changes that take place in animal improvement programs. The Virginia chicken lines have for more than 50 years been subjected to single-trait, bi-directional, divergent selection for high and low juvenile body weight. It is one of the most well studied experimental populations in agricultural animals and has played an instrumental role in the understanding of the genetic basis of complex traits. In this paper, we summarize the findings from the more recent publications focusing on the efforts to identify the loci contributing to selection response as well as discuss the currently ongoing research. We conclude by describing some future research prospects that promise to bring new, interesting insights into the biology of complex traits in the near future and their implications for future animal improvement programs.

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Main Authors: Pettersson,Mats E., Carlborg,Örjan
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Zootecnia 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982010001300028
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spelling oai:scielo:S1516-359820100013000282010-08-09Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken linesPettersson,Mats E.Carlborg,Örjan body weight chicken epistasis metabolic QTL selection Long-term selection experiments provide a valuable resource for understanding the genetic changes that take place in animal improvement programs. The Virginia chicken lines have for more than 50 years been subjected to single-trait, bi-directional, divergent selection for high and low juvenile body weight. It is one of the most well studied experimental populations in agricultural animals and has played an instrumental role in the understanding of the genetic basis of complex traits. In this paper, we summarize the findings from the more recent publications focusing on the efforts to identify the loci contributing to selection response as well as discuss the currently ongoing research. We conclude by describing some future research prospects that promise to bring new, interesting insights into the biology of complex traits in the near future and their implications for future animal improvement programs.info:eu-repo/semantics/openAccessSociedade Brasileira de ZootecniaRevista Brasileira de Zootecnia v.39 suppl.spe 20102010-07-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982010001300028en10.1590/S1516-35982010001300028
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country Brasil
countrycode BR
component Revista
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region America del Sur
libraryname SciELO
language English
format Digital
author Pettersson,Mats E.
Carlborg,Örjan
spellingShingle Pettersson,Mats E.
Carlborg,Örjan
Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines
author_facet Pettersson,Mats E.
Carlborg,Örjan
author_sort Pettersson,Mats E.
title Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines
title_short Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines
title_full Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines
title_fullStr Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines
title_full_unstemmed Dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the Virginia chicken lines
title_sort dissecting the genetic architecture of complex traits and its impact on genetic improvement programs: lessons learnt from the virginia chicken lines
description Long-term selection experiments provide a valuable resource for understanding the genetic changes that take place in animal improvement programs. The Virginia chicken lines have for more than 50 years been subjected to single-trait, bi-directional, divergent selection for high and low juvenile body weight. It is one of the most well studied experimental populations in agricultural animals and has played an instrumental role in the understanding of the genetic basis of complex traits. In this paper, we summarize the findings from the more recent publications focusing on the efforts to identify the loci contributing to selection response as well as discuss the currently ongoing research. We conclude by describing some future research prospects that promise to bring new, interesting insights into the biology of complex traits in the near future and their implications for future animal improvement programs.
publisher Sociedade Brasileira de Zootecnia
publishDate 2010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982010001300028
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AT carlborgorjan dissectingthegeneticarchitectureofcomplextraitsanditsimpactongeneticimprovementprogramslessonslearntfromthevirginiachickenlines
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