Perioperative frozen section examination in parotid gland tumors

CONTEXT: The minimal recommended surgical approach to parotid tumors is partial parotidectomy with resection of the superficial lobe of the gland. Histologic diagnosis prior to surgery is not possible, as incisional biopsies are contraindicated due to the possibility of facial nerve injury or incomplete tumor resection. Thus, the biopsies tend to be perioperative. OBJECTIVE: To compare the results of frozen section examination with the definitive pathological diagnosis. DESIGN: Accuracy study by retrospective analysis. SETTING: Head and Neck Surgery Service of Heliópolis Hospital, São Paulo, Brazil. SAMPLE: 153 cases of parotid gland tumors treated between 1977 and 1994. DIAGNOSTIC TEST: Frozen section and pathological diagnosis. MAIN MEASUREMENTS: Sensibility and specificity of the frozen section examination. RESULTS: Frozen section study diagnosed 19 (12.4%) malignant and 127 (83.7%) benign tumors. Sensitivity of the frozen sections for malignancy was 61.5% (95% CI 54 to 69%) and specificity was 98% (95% CI 94 to 100%), and this result is comparable to the literature. CONCLUSIONS: We consider that frozen section examination for salivary gland tumors is not sufficient on its own for deciding on the best management. Their interpretation must be correlated with clinical and intraoperative findings, in association with the surgeon's experience.

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Main Authors: Carvalho,Marcos Brasilino de, Soares,João Marcos Arantes, Rapoport,Abrão, Andrade Sobrinho,Josias de, Fava,Antonio Sérgio, Kanda,Jossi Ledo, Lehn,Carlos Neutzling, Walder,Fernando, Menezes,Marcelo Benedito, Negri,Sérgio Luiz Coelho
Format: Digital revista
Language:English
Published: Associação Paulista de Medicina - APM 1999
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000600002
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spelling oai:scielo:S1516-318019990006000022000-01-06Perioperative frozen section examination in parotid gland tumorsCarvalho,Marcos Brasilino deSoares,João Marcos ArantesRapoport,AbrãoAndrade Sobrinho,Josias deFava,Antonio SérgioKanda,Jossi LedoLehn,Carlos NeutzlingWalder,FernandoMenezes,Marcelo BeneditoNegri,Sérgio Luiz Coelho Frozen section Head and Neck tumors Parotid gland tumors Salivary gland tumors CONTEXT: The minimal recommended surgical approach to parotid tumors is partial parotidectomy with resection of the superficial lobe of the gland. Histologic diagnosis prior to surgery is not possible, as incisional biopsies are contraindicated due to the possibility of facial nerve injury or incomplete tumor resection. Thus, the biopsies tend to be perioperative. OBJECTIVE: To compare the results of frozen section examination with the definitive pathological diagnosis. DESIGN: Accuracy study by retrospective analysis. SETTING: Head and Neck Surgery Service of Heliópolis Hospital, São Paulo, Brazil. SAMPLE: 153 cases of parotid gland tumors treated between 1977 and 1994. DIAGNOSTIC TEST: Frozen section and pathological diagnosis. MAIN MEASUREMENTS: Sensibility and specificity of the frozen section examination. RESULTS: Frozen section study diagnosed 19 (12.4%) malignant and 127 (83.7%) benign tumors. Sensitivity of the frozen sections for malignancy was 61.5% (95% CI 54 to 69%) and specificity was 98% (95% CI 94 to 100%), and this result is comparable to the literature. CONCLUSIONS: We consider that frozen section examination for salivary gland tumors is not sufficient on its own for deciding on the best management. Their interpretation must be correlated with clinical and intraoperative findings, in association with the surgeon's experience.info:eu-repo/semantics/openAccessAssociação Paulista de Medicina - APMSao Paulo Medical Journal v.117 n.6 19991999-11-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000600002en10.1590/S1516-31801999000600002
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libraryname SciELO
language English
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author Carvalho,Marcos Brasilino de
Soares,João Marcos Arantes
Rapoport,Abrão
Andrade Sobrinho,Josias de
Fava,Antonio Sérgio
Kanda,Jossi Ledo
Lehn,Carlos Neutzling
Walder,Fernando
Menezes,Marcelo Benedito
Negri,Sérgio Luiz Coelho
spellingShingle Carvalho,Marcos Brasilino de
Soares,João Marcos Arantes
Rapoport,Abrão
Andrade Sobrinho,Josias de
Fava,Antonio Sérgio
Kanda,Jossi Ledo
Lehn,Carlos Neutzling
Walder,Fernando
Menezes,Marcelo Benedito
Negri,Sérgio Luiz Coelho
Perioperative frozen section examination in parotid gland tumors
author_facet Carvalho,Marcos Brasilino de
Soares,João Marcos Arantes
Rapoport,Abrão
Andrade Sobrinho,Josias de
Fava,Antonio Sérgio
Kanda,Jossi Ledo
Lehn,Carlos Neutzling
Walder,Fernando
Menezes,Marcelo Benedito
Negri,Sérgio Luiz Coelho
author_sort Carvalho,Marcos Brasilino de
title Perioperative frozen section examination in parotid gland tumors
title_short Perioperative frozen section examination in parotid gland tumors
title_full Perioperative frozen section examination in parotid gland tumors
title_fullStr Perioperative frozen section examination in parotid gland tumors
title_full_unstemmed Perioperative frozen section examination in parotid gland tumors
title_sort perioperative frozen section examination in parotid gland tumors
description CONTEXT: The minimal recommended surgical approach to parotid tumors is partial parotidectomy with resection of the superficial lobe of the gland. Histologic diagnosis prior to surgery is not possible, as incisional biopsies are contraindicated due to the possibility of facial nerve injury or incomplete tumor resection. Thus, the biopsies tend to be perioperative. OBJECTIVE: To compare the results of frozen section examination with the definitive pathological diagnosis. DESIGN: Accuracy study by retrospective analysis. SETTING: Head and Neck Surgery Service of Heliópolis Hospital, São Paulo, Brazil. SAMPLE: 153 cases of parotid gland tumors treated between 1977 and 1994. DIAGNOSTIC TEST: Frozen section and pathological diagnosis. MAIN MEASUREMENTS: Sensibility and specificity of the frozen section examination. RESULTS: Frozen section study diagnosed 19 (12.4%) malignant and 127 (83.7%) benign tumors. Sensitivity of the frozen sections for malignancy was 61.5% (95% CI 54 to 69%) and specificity was 98% (95% CI 94 to 100%), and this result is comparable to the literature. CONCLUSIONS: We consider that frozen section examination for salivary gland tumors is not sufficient on its own for deciding on the best management. Their interpretation must be correlated with clinical and intraoperative findings, in association with the surgeon's experience.
publisher Associação Paulista de Medicina - APM
publishDate 1999
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000600002
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