Astaxanthin: structural and functional aspects

Astaxanthin, a carotenoid belonging to the xanthophyll class, has stirred great interest due to its antioxidant capacity and its possible role in reducing the risk of some diseases. Astaxanthin occurs naturally in microalgae, such as Haematococcus pluvialis and the yeast Phaffia rhodozyma, and has also been considered to be the major carotenoid in salmon and crustaceans. Shrimp processing waste, which is generally discarded, is also an important source of astaxanthin. The antioxidant activity of astaxanthin has been observed to modulate biological functions related to lipid peroxidation, having beneficial effects on chronic diseases such as cardiovascular disease, macular degeneration and cancer. Researches have shown that both astaxanthin obtained from natural sources and its synthetic counterpart produce satisfactory effects, but studies in humans are limited to natural sources. There is no established nutritional recommendation regarding astaxanthin daily intake but most studies reported beneficial results from a daily intake of 4mg. Thus, this review discusses some aspects of the carotenoid astaxanthin, highlighting its chemical structure and antioxidant activity, and some studies that report its use in humans.

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Main Authors: Seabra,Larissa Mont'Alverne Jucá, Pedrosa,Lucia Fátima Campos
Format: Digital revista
Language:English
Published: Pontifícia Universidade Católica de Campinas 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732010000600010
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spelling oai:scielo:S1415-527320100006000102011-04-20Astaxanthin: structural and functional aspectsSeabra,Larissa Mont'Alverne JucáPedrosa,Lucia Fátima Campos Antioxidants Astaxanthin Carotenoids Chronic diseases Astaxanthin, a carotenoid belonging to the xanthophyll class, has stirred great interest due to its antioxidant capacity and its possible role in reducing the risk of some diseases. Astaxanthin occurs naturally in microalgae, such as Haematococcus pluvialis and the yeast Phaffia rhodozyma, and has also been considered to be the major carotenoid in salmon and crustaceans. Shrimp processing waste, which is generally discarded, is also an important source of astaxanthin. The antioxidant activity of astaxanthin has been observed to modulate biological functions related to lipid peroxidation, having beneficial effects on chronic diseases such as cardiovascular disease, macular degeneration and cancer. Researches have shown that both astaxanthin obtained from natural sources and its synthetic counterpart produce satisfactory effects, but studies in humans are limited to natural sources. There is no established nutritional recommendation regarding astaxanthin daily intake but most studies reported beneficial results from a daily intake of 4mg. Thus, this review discusses some aspects of the carotenoid astaxanthin, highlighting its chemical structure and antioxidant activity, and some studies that report its use in humans.info:eu-repo/semantics/openAccessPontifícia Universidade Católica de CampinasRevista de Nutrição v.23 n.6 20102010-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732010000600010en10.1590/S1415-52732010000600010
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country Brasil
countrycode BR
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libraryname SciELO
language English
format Digital
author Seabra,Larissa Mont'Alverne Jucá
Pedrosa,Lucia Fátima Campos
spellingShingle Seabra,Larissa Mont'Alverne Jucá
Pedrosa,Lucia Fátima Campos
Astaxanthin: structural and functional aspects
author_facet Seabra,Larissa Mont'Alverne Jucá
Pedrosa,Lucia Fátima Campos
author_sort Seabra,Larissa Mont'Alverne Jucá
title Astaxanthin: structural and functional aspects
title_short Astaxanthin: structural and functional aspects
title_full Astaxanthin: structural and functional aspects
title_fullStr Astaxanthin: structural and functional aspects
title_full_unstemmed Astaxanthin: structural and functional aspects
title_sort astaxanthin: structural and functional aspects
description Astaxanthin, a carotenoid belonging to the xanthophyll class, has stirred great interest due to its antioxidant capacity and its possible role in reducing the risk of some diseases. Astaxanthin occurs naturally in microalgae, such as Haematococcus pluvialis and the yeast Phaffia rhodozyma, and has also been considered to be the major carotenoid in salmon and crustaceans. Shrimp processing waste, which is generally discarded, is also an important source of astaxanthin. The antioxidant activity of astaxanthin has been observed to modulate biological functions related to lipid peroxidation, having beneficial effects on chronic diseases such as cardiovascular disease, macular degeneration and cancer. Researches have shown that both astaxanthin obtained from natural sources and its synthetic counterpart produce satisfactory effects, but studies in humans are limited to natural sources. There is no established nutritional recommendation regarding astaxanthin daily intake but most studies reported beneficial results from a daily intake of 4mg. Thus, this review discusses some aspects of the carotenoid astaxanthin, highlighting its chemical structure and antioxidant activity, and some studies that report its use in humans.
publisher Pontifícia Universidade Católica de Campinas
publishDate 2010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732010000600010
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