Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene
Abstract Musicality is defined as a natural tendency, sensibility, knowledge, or talent to create, perceive, and play music. Musical abilities involve a great range of social and cognitive behaviors, which are influenced by both environmental and genetic factors. Although a number of studies have yielded insights into music genetics research, genes and biological pathways related to these traits are not fully understood. Our hypothesis in the current study is that genes associated with different behaviors could also influence the musical phenotype. Our aim was to investigate whether polymorphisms in six genes (AVPR1A, SLC6A4, ITGB3, COMT, DRD2 and DRD4) related to social and cognitive traits are associated with musicality in a sample of children. Musicality was assessed through an individualized music therapy assessment profile (IMTAP) which has been validated in Brazil to measure musical ability. We show here that the RS1 microsatellite of the AVPR1A gene is nominally associated with musicality, corroborating previous results linking AVPR1A with musical activity. This study is one of the first to investigate musicality in a comprehensive way, and it contributes to better understand the genetic basis underlying musical ability.
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Genética
2017
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300421 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S1415-47572017000300421 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S1415-475720170003004212017-06-28Music genetics research: Association with musicality of a polymorphism in the AVPR1A geneMariath,Luiza MonteavaroSilva,Alexandre Mauat daKowalski,Thayne WoycinckGattino,Gustavo SchulzAraujo,Gustavo Andrade deFigueiredo,Felipe GrahlTagliani-Ribeiro,AliceRoman,TatianaVianna,Fernanda Sales LuizSchuler-Faccini,LavíniaSchuch,Jaqueline Bohrer musicality music vasopressin AVPR1A Abstract Musicality is defined as a natural tendency, sensibility, knowledge, or talent to create, perceive, and play music. Musical abilities involve a great range of social and cognitive behaviors, which are influenced by both environmental and genetic factors. Although a number of studies have yielded insights into music genetics research, genes and biological pathways related to these traits are not fully understood. Our hypothesis in the current study is that genes associated with different behaviors could also influence the musical phenotype. Our aim was to investigate whether polymorphisms in six genes (AVPR1A, SLC6A4, ITGB3, COMT, DRD2 and DRD4) related to social and cognitive traits are associated with musicality in a sample of children. Musicality was assessed through an individualized music therapy assessment profile (IMTAP) which has been validated in Brazil to measure musical ability. We show here that the RS1 microsatellite of the AVPR1A gene is nominally associated with musicality, corroborating previous results linking AVPR1A with musical activity. This study is one of the first to investigate musicality in a comprehensive way, and it contributes to better understand the genetic basis underlying musical ability.info:eu-repo/semantics/openAccessSociedade Brasileira de GenéticaGenetics and Molecular Biology v.40 n.2 20172017-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300421en10.1590/1678-4685-gmb-2016-0021 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Mariath,Luiza Monteavaro Silva,Alexandre Mauat da Kowalski,Thayne Woycinck Gattino,Gustavo Schulz Araujo,Gustavo Andrade de Figueiredo,Felipe Grahl Tagliani-Ribeiro,Alice Roman,Tatiana Vianna,Fernanda Sales Luiz Schuler-Faccini,Lavínia Schuch,Jaqueline Bohrer |
spellingShingle |
Mariath,Luiza Monteavaro Silva,Alexandre Mauat da Kowalski,Thayne Woycinck Gattino,Gustavo Schulz Araujo,Gustavo Andrade de Figueiredo,Felipe Grahl Tagliani-Ribeiro,Alice Roman,Tatiana Vianna,Fernanda Sales Luiz Schuler-Faccini,Lavínia Schuch,Jaqueline Bohrer Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene |
author_facet |
Mariath,Luiza Monteavaro Silva,Alexandre Mauat da Kowalski,Thayne Woycinck Gattino,Gustavo Schulz Araujo,Gustavo Andrade de Figueiredo,Felipe Grahl Tagliani-Ribeiro,Alice Roman,Tatiana Vianna,Fernanda Sales Luiz Schuler-Faccini,Lavínia Schuch,Jaqueline Bohrer |
author_sort |
Mariath,Luiza Monteavaro |
title |
Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene |
title_short |
Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene |
title_full |
Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene |
title_fullStr |
Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene |
title_full_unstemmed |
Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene |
title_sort |
music genetics research: association with musicality of a polymorphism in the avpr1a gene |
description |
Abstract Musicality is defined as a natural tendency, sensibility, knowledge, or talent to create, perceive, and play music. Musical abilities involve a great range of social and cognitive behaviors, which are influenced by both environmental and genetic factors. Although a number of studies have yielded insights into music genetics research, genes and biological pathways related to these traits are not fully understood. Our hypothesis in the current study is that genes associated with different behaviors could also influence the musical phenotype. Our aim was to investigate whether polymorphisms in six genes (AVPR1A, SLC6A4, ITGB3, COMT, DRD2 and DRD4) related to social and cognitive traits are associated with musicality in a sample of children. Musicality was assessed through an individualized music therapy assessment profile (IMTAP) which has been validated in Brazil to measure musical ability. We show here that the RS1 microsatellite of the AVPR1A gene is nominally associated with musicality, corroborating previous results linking AVPR1A with musical activity. This study is one of the first to investigate musicality in a comprehensive way, and it contributes to better understand the genetic basis underlying musical ability. |
publisher |
Sociedade Brasileira de Genética |
publishDate |
2017 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300421 |
work_keys_str_mv |
AT mariathluizamonteavaro musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT silvaalexandremauatda musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT kowalskithaynewoycinck musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT gattinogustavoschulz musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT araujogustavoandradede musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT figueiredofelipegrahl musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT taglianiribeiroalice musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT romantatiana musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT viannafernandasalesluiz musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT schulerfaccinilavinia musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene AT schuchjaquelinebohrer musicgeneticsresearchassociationwithmusicalityofapolymorphismintheavpr1agene |
_version_ |
1756419246908243968 |