SARS-CoV-2 leading to acute pancreatitis: an unusual presentation

SARS-CoV-2 leading to acute pancreatitis: an unusual presentation

ABSTRACT During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Angiotensin-converting enzyme-2, the functional virus host cell receptor expressed by organs and tissues, seems to have an important role in the pathophysiology and presentation of this disease. In pancreas, this receptor is expressed in both exocrine glands and islets, being a potential target for the virus and subsequent pancreatic injury. There are few articles reporting pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis.

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Main Authors: Alves,Amanda Mandarino, Yvamoto,Erika Yuki, Marzinotto,Maira Andrade Nacimbem, Teixeira,Ana Cristina de Sá, Carrilho,Flair José
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000600561
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spelling oai:scielo:S1413-867020200006005612021-01-13SARS-CoV-2 leading to acute pancreatitis: an unusual presentationAlves,Amanda MandarinoYvamoto,Erika YukiMarzinotto,Maira Andrade NacimbemTeixeira,Ana Cristina de SáCarrilho,Flair José COVID-19 SARS-CoV-2 Acute pancreatitis ABSTRACT During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Angiotensin-converting enzyme-2, the functional virus host cell receptor expressed by organs and tissues, seems to have an important role in the pathophysiology and presentation of this disease. In pancreas, this receptor is expressed in both exocrine glands and islets, being a potential target for the virus and subsequent pancreatic injury. There are few articles reporting pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.24 n.6 20202020-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000600561en10.1016/j.bjid.2020.08.011
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Alves,Amanda Mandarino
Yvamoto,Erika Yuki
Marzinotto,Maira Andrade Nacimbem
Teixeira,Ana Cristina de Sá
Carrilho,Flair José
spellingShingle Alves,Amanda Mandarino
Yvamoto,Erika Yuki
Marzinotto,Maira Andrade Nacimbem
Teixeira,Ana Cristina de Sá
Carrilho,Flair José
SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
author_facet Alves,Amanda Mandarino
Yvamoto,Erika Yuki
Marzinotto,Maira Andrade Nacimbem
Teixeira,Ana Cristina de Sá
Carrilho,Flair José
author_sort Alves,Amanda Mandarino
title SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
title_short SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
title_full SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
title_fullStr SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
title_full_unstemmed SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
title_sort sars-cov-2 leading to acute pancreatitis: an unusual presentation
description ABSTRACT During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Angiotensin-converting enzyme-2, the functional virus host cell receptor expressed by organs and tissues, seems to have an important role in the pathophysiology and presentation of this disease. In pancreas, this receptor is expressed in both exocrine glands and islets, being a potential target for the virus and subsequent pancreatic injury. There are few articles reporting pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis.
publisher Brazilian Society of Infectious Diseases
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000600561
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AT marzinottomairaandradenacimbem sarscov2leadingtoacutepancreatitisanunusualpresentation
AT teixeiraanacristinadesa sarscov2leadingtoacutepancreatitisanunusualpresentation
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