Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil
ABSTRACT The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012. A total of 529 serum samples were analyzed by enzyme-linked immunosorbent assay for detecting IgG antibodies against T. solium larvae, and Western blotting was used for confirming the diagnosis through the recognition of at least two specific peptides from their serum antibodies. The 351/529 (66.3%) reactive samples were analyzed by enzyme-linked immunosorbent assay and Western blotting confirmed the diagnosis in 73 samples that recognized at least two of the following peptides specific IgG antibodies for cysticercosis: 18, 24, 28–32, 39–42, 47–52, 64–68, and 70 kDa. The seroprevalence of cysticercosis was 13.8% (95% CI 5.9–21.7), demonstrating that the studied area is endemic to this disease.
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Brazilian Society of Infectious Diseases
2018
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oai:scielo:S1413-867020180002001462018-05-22Seroprevalence of human cysticercosis in Jataí, Goiás state, BrazilGuarda,Kaliny Xavier daCosta-Cruz,Julia MariaBarcelos,Ivanildes Solange da Costa Cysticercosis Taenia solium Epidemiology Diagnosis Brazil ABSTRACT The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012. A total of 529 serum samples were analyzed by enzyme-linked immunosorbent assay for detecting IgG antibodies against T. solium larvae, and Western blotting was used for confirming the diagnosis through the recognition of at least two specific peptides from their serum antibodies. The 351/529 (66.3%) reactive samples were analyzed by enzyme-linked immunosorbent assay and Western blotting confirmed the diagnosis in 73 samples that recognized at least two of the following peptides specific IgG antibodies for cysticercosis: 18, 24, 28–32, 39–42, 47–52, 64–68, and 70 kDa. The seroprevalence of cysticercosis was 13.8% (95% CI 5.9–21.7), demonstrating that the studied area is endemic to this disease.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.22 n.2 20182018-03-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200146en10.1016/j.bjid.2018.01.002 |
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Guarda,Kaliny Xavier da Costa-Cruz,Julia Maria Barcelos,Ivanildes Solange da Costa |
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Guarda,Kaliny Xavier da Costa-Cruz,Julia Maria Barcelos,Ivanildes Solange da Costa Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| author_facet |
Guarda,Kaliny Xavier da Costa-Cruz,Julia Maria Barcelos,Ivanildes Solange da Costa |
| author_sort |
Guarda,Kaliny Xavier da |
| title |
Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_short |
Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_full |
Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_fullStr |
Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_full_unstemmed |
Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil |
| title_sort |
seroprevalence of human cysticercosis in jataí, goiás state, brazil |
| description |
ABSTRACT The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012. A total of 529 serum samples were analyzed by enzyme-linked immunosorbent assay for detecting IgG antibodies against T. solium larvae, and Western blotting was used for confirming the diagnosis through the recognition of at least two specific peptides from their serum antibodies. The 351/529 (66.3%) reactive samples were analyzed by enzyme-linked immunosorbent assay and Western blotting confirmed the diagnosis in 73 samples that recognized at least two of the following peptides specific IgG antibodies for cysticercosis: 18, 24, 28–32, 39–42, 47–52, 64–68, and 70 kDa. The seroprevalence of cysticercosis was 13.8% (95% CI 5.9–21.7), demonstrating that the studied area is endemic to this disease. |
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Brazilian Society of Infectious Diseases |
| publishDate |
2018 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200146 |
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