Hepatitis C: a critical analysis of therapeutic response predictors

Hepatitis C: a critical analysis of therapeutic response predictors

Treatment of chronic hepatitis C is still unspecific. However, there is great expectancy concerning the new pegylated interferons. As there has been much controversy about the best parameters to determine whether treatment is effective, we analyzed several criteria currently used for evaluation, including serum alanine aminotransferase (ALT) normalization, viral load reduction and improvement of hepatic histology.

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Main Authors: Focaccia,R., Siciliano,R.F., Santos,E.D.B., Boccardo,E., Conceição,O.J.G., Barbosa,U.O., Galante,V.C.
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2002
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200003
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spelling oai:scielo:S1413-867020020002000032003-03-25Hepatitis C: a critical analysis of therapeutic response predictorsFocaccia,R.Siciliano,R.F.Santos,E.D.B.Boccardo,E.Conceição,O.J.G.Barbosa,U.O.Galante,V.C. ALT normalization hepatitis C viral load reduction Treatment of chronic hepatitis C is still unspecific. However, there is great expectancy concerning the new pegylated interferons. As there has been much controversy about the best parameters to determine whether treatment is effective, we analyzed several criteria currently used for evaluation, including serum alanine aminotransferase (ALT) normalization, viral load reduction and improvement of hepatic histology.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.6 n.2 20022002-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200003en10.1590/S1413-86702002000200003
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country Brasil
countrycode BR
component Revista
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region America del Sur
libraryname SciELO
language English
format Digital
author Focaccia,R.
Siciliano,R.F.
Santos,E.D.B.
Boccardo,E.
Conceição,O.J.G.
Barbosa,U.O.
Galante,V.C.
spellingShingle Focaccia,R.
Siciliano,R.F.
Santos,E.D.B.
Boccardo,E.
Conceição,O.J.G.
Barbosa,U.O.
Galante,V.C.
Hepatitis C: a critical analysis of therapeutic response predictors
author_facet Focaccia,R.
Siciliano,R.F.
Santos,E.D.B.
Boccardo,E.
Conceição,O.J.G.
Barbosa,U.O.
Galante,V.C.
author_sort Focaccia,R.
title Hepatitis C: a critical analysis of therapeutic response predictors
title_short Hepatitis C: a critical analysis of therapeutic response predictors
title_full Hepatitis C: a critical analysis of therapeutic response predictors
title_fullStr Hepatitis C: a critical analysis of therapeutic response predictors
title_full_unstemmed Hepatitis C: a critical analysis of therapeutic response predictors
title_sort hepatitis c: a critical analysis of therapeutic response predictors
description Treatment of chronic hepatitis C is still unspecific. However, there is great expectancy concerning the new pegylated interferons. As there has been much controversy about the best parameters to determine whether treatment is effective, we analyzed several criteria currently used for evaluation, including serum alanine aminotransferase (ALT) normalization, viral load reduction and improvement of hepatic histology.
publisher Brazilian Society of Infectious Diseases
publishDate 2002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200003
work_keys_str_mv AT focacciar hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT sicilianorf hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT santosedb hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT boccardoe hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT conceicaoojg hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT barbosauo hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT galantevc hepatitiscacriticalanalysisoftherapeuticresponsepredictors
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