Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model
Abstract In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. The stent platform was cobalt-chromium L605 (Co-Cr), with struts thickness of 80 μm, balloon expandable. We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. We succeeded in efficacy and safety of the device after fluoroscopy-guided implant proving excellent capacity of release system, traceability, fluoroscopic visualization, symmetric expansion, and complete endothelial attach. Furthermore, we obtained a good post-implant balloon withdrawal, functional integrity, and no vascular complications. We observed adequate clinical evolution 3 weeks after the stent implantation.
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Instituto Nacional de Cardiología Ignacio Chávez
2020
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oai:scielo:S1405-994020200002001422020-10-20Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal modelAbundes-Velasco,ArturoJiménez-Rodríguez,Gian M.Romero-Ibarra,José L.Sandoval-Jones,Juan P.Sánchez-Pérez,EfraínGalaz-Méndez,RamsésUlacia-Flores,PaolaFarjat-Pasos,Julio I.Padilla-Ibarra,JorgeAceves-Díaz González,SebastiánMartínez-Ríos,Marco A.Peña-Duque,Marco A.Rodriguez-Parra,David A. Stent Novel bare metal stent Myocardial infarction Percutaneous coronary intervention Abstract In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. The stent platform was cobalt-chromium L605 (Co-Cr), with struts thickness of 80 μm, balloon expandable. We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. We succeeded in efficacy and safety of the device after fluoroscopy-guided implant proving excellent capacity of release system, traceability, fluoroscopic visualization, symmetric expansion, and complete endothelial attach. Furthermore, we obtained a good post-implant balloon withdrawal, functional integrity, and no vascular complications. We observed adequate clinical evolution 3 weeks after the stent implantation.info:eu-repo/semantics/openAccessInstituto Nacional de Cardiología Ignacio ChávezArchivos de cardiología de México v.90 n.2 20202020-06-01info:eu-repo/semantics/articletext/htmlhttp://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-99402020000200142en10.24875/acme.m20000108 |
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Abundes-Velasco,Arturo Jiménez-Rodríguez,Gian M. Romero-Ibarra,José L. Sandoval-Jones,Juan P. Sánchez-Pérez,Efraín Galaz-Méndez,Ramsés Ulacia-Flores,Paola Farjat-Pasos,Julio I. Padilla-Ibarra,Jorge Aceves-Díaz González,Sebastián Martínez-Ríos,Marco A. Peña-Duque,Marco A. Rodriguez-Parra,David A. |
spellingShingle |
Abundes-Velasco,Arturo Jiménez-Rodríguez,Gian M. Romero-Ibarra,José L. Sandoval-Jones,Juan P. Sánchez-Pérez,Efraín Galaz-Méndez,Ramsés Ulacia-Flores,Paola Farjat-Pasos,Julio I. Padilla-Ibarra,Jorge Aceves-Díaz González,Sebastián Martínez-Ríos,Marco A. Peña-Duque,Marco A. Rodriguez-Parra,David A. Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model |
author_facet |
Abundes-Velasco,Arturo Jiménez-Rodríguez,Gian M. Romero-Ibarra,José L. Sandoval-Jones,Juan P. Sánchez-Pérez,Efraín Galaz-Méndez,Ramsés Ulacia-Flores,Paola Farjat-Pasos,Julio I. Padilla-Ibarra,Jorge Aceves-Díaz González,Sebastián Martínez-Ríos,Marco A. Peña-Duque,Marco A. Rodriguez-Parra,David A. |
author_sort |
Abundes-Velasco,Arturo |
title |
Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model |
title_short |
Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model |
title_full |
Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model |
title_fullStr |
Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model |
title_full_unstemmed |
Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model |
title_sort |
design and manufacture of a coronary stent inc-1 and initial tests in experimental animal model |
description |
Abstract In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. The stent platform was cobalt-chromium L605 (Co-Cr), with struts thickness of 80 μm, balloon expandable. We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. We succeeded in efficacy and safety of the device after fluoroscopy-guided implant proving excellent capacity of release system, traceability, fluoroscopic visualization, symmetric expansion, and complete endothelial attach. Furthermore, we obtained a good post-implant balloon withdrawal, functional integrity, and no vascular complications. We observed adequate clinical evolution 3 weeks after the stent implantation. |
publisher |
Instituto Nacional de Cardiología Ignacio Chávez |
publishDate |
2020 |
url |
http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-99402020000200142 |
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