Giant cell glioblastoma: review of the literature and illustrated case

Giant cell glioblastoma: review of the literature and illustrated case

Giant cell glioblastoma is an infrequent variety of glioblastoma (5% of the cases). It has deserved a separate category in the World Health Organization classification of grade IV tumors. The clinical, imaging, histological and immunohistochemical characteristics, and the genetic alterations are reviewed. Treatment and prognosis are discussed and updated. The case of a patient that survived 19 months and died of spinal leptomeningeal metastases is illustrated.

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Main Authors: Valle-Folgueral,J.M., Mascarenhas,L., Costa,J.A., Vieira,F., Soares-Fernandes,J., Beleza,P., Alegria,C.
Format: Digital revista
Language:English
Published: Sociedad Española de Neurocirugía 2008
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-14732008000400005
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spelling oai:scielo:S1130-147320080004000052008-10-01Giant cell glioblastoma: review of the literature and illustrated caseValle-Folgueral,J.M.Mascarenhas,L.Costa,J.A.Vieira,F.Soares-Fernandes,J.Beleza,P.Alegria,C. Giant cell glioblastoma Leptomeningeal metastases Surgery Temozolomide Radiotherapy Giant cell glioblastoma is an infrequent variety of glioblastoma (5% of the cases). It has deserved a separate category in the World Health Organization classification of grade IV tumors. The clinical, imaging, histological and immunohistochemical characteristics, and the genetic alterations are reviewed. Treatment and prognosis are discussed and updated. The case of a patient that survived 19 months and died of spinal leptomeningeal metastases is illustrated.Sociedad Española de NeurocirugíaNeurocirugía v.19 n.4 20082008-08-01journal articletext/htmlhttp://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-14732008000400005en
institution SCIELO
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country España
countrycode ES
component Revista
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databasecode rev-scielo-es
tag revista
region Europa del Sur
libraryname SciELO
language English
format Digital
author Valle-Folgueral,J.M.
Mascarenhas,L.
Costa,J.A.
Vieira,F.
Soares-Fernandes,J.
Beleza,P.
Alegria,C.
spellingShingle Valle-Folgueral,J.M.
Mascarenhas,L.
Costa,J.A.
Vieira,F.
Soares-Fernandes,J.
Beleza,P.
Alegria,C.
Giant cell glioblastoma: review of the literature and illustrated case
author_facet Valle-Folgueral,J.M.
Mascarenhas,L.
Costa,J.A.
Vieira,F.
Soares-Fernandes,J.
Beleza,P.
Alegria,C.
author_sort Valle-Folgueral,J.M.
title Giant cell glioblastoma: review of the literature and illustrated case
title_short Giant cell glioblastoma: review of the literature and illustrated case
title_full Giant cell glioblastoma: review of the literature and illustrated case
title_fullStr Giant cell glioblastoma: review of the literature and illustrated case
title_full_unstemmed Giant cell glioblastoma: review of the literature and illustrated case
title_sort giant cell glioblastoma: review of the literature and illustrated case
description Giant cell glioblastoma is an infrequent variety of glioblastoma (5% of the cases). It has deserved a separate category in the World Health Organization classification of grade IV tumors. The clinical, imaging, histological and immunohistochemical characteristics, and the genetic alterations are reviewed. Treatment and prognosis are discussed and updated. The case of a patient that survived 19 months and died of spinal leptomeningeal metastases is illustrated.
publisher Sociedad Española de Neurocirugía
publishDate 2008
url http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-14732008000400005
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AT vieiraf giantcellglioblastomareviewoftheliteratureandillustratedcase
AT soaresfernandesj giantcellglioblastomareviewoftheliteratureandillustratedcase
AT belezap giantcellglioblastomareviewoftheliteratureandillustratedcase
AT alegriac giantcellglioblastomareviewoftheliteratureandillustratedcase
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