Severe ischemic colitis following olanzapine use: a Case Report

Ischemic colitis is the most common subtype of intestinal ischemia usually resulting from vasospasm, vessel occlusion or mesenteric hypoperfusion. Neuroleptics have seldom been linked to ischemic colitis by blocking peripheral anticholinergic and antiserotonergic receptors inducing severe gastrointestinal paresis. We report a young patient with severe ischemic colitis requiring surgery due to necrosis of the bowel. After exclusion of other potential causes, olanzapine was admitted as the cause of ischemia. Clinicians should be aware of how to recognize and treat the potentially life-threatening effects of neuroleptics.

Saved in:
Bibliographic Details
Main Authors: Fernandes,Samuel Raimundo, Alves,Rosa, Araújo Correia,Luís, Gonçalves,Ana Rita, Malaquias,João, Oliveira,Emília, Velosa,José
Format: Digital revista
Language:English
Published: Sociedad Española de Patología Digestiva 2016
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000900018
Tags: Add Tag
No Tags, Be the first to tag this record!