Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure

Gastrointestinal bleeding of obscure origin or with an intractable cause is particularly common in patients with atrial fibrillation subject to oral anticoagulant therapy. This condition is highly recurrent and therefore gives rise to high morbidity and mortality rates, thus entailing a vicious cycle that is difficult to solve. Percutaneous left atrial appendage closure has become a therapeutic alternative for patients with atrial fibrillation and a contraindication for oral anticoagulation. This technique would allow the discontinuation of oral anticoagulants, thus helping to reduce the risk for gastrointestinal bleeding, and would also be protective against embolic events in this group of patients, thereby eventually breaking this vicious cycle. We report our experience with percutaneous left atrial appendage closure in the management of patients with atrial fibrillation who are subject to oral anticoagulation therapy and suffer from obscure or intractable gastrointestinal bleeding.

Saved in:
Bibliographic Details
Main Authors: Fernández-Rodríguez,Diego, Martín-Yuste,Victoria, Feu,Faust, Brugaletta,Salvatore, Freixa,Xavier, Regueiro,Ander, Sabaté,Manel
Format: Digital revista
Language:English
Published: Sociedad Española de Patología Digestiva 2014
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082014000500009
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S1130-01082014000500009
record_format ojs
spelling oai:scielo:S1130-010820140005000092015-01-20Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closureFernández-Rodríguez,DiegoMartín-Yuste,VictoriaFeu,FaustBrugaletta,SalvatoreFreixa,XavierRegueiro,AnderSabaté,Manel Atrial fibrillation Oral anticoagulants Obscure gastrointestinal bleeding Intractable gastrointestinal bleeding Percutaneous left atrial appendage closure Gastrointestinal bleeding of obscure origin or with an intractable cause is particularly common in patients with atrial fibrillation subject to oral anticoagulant therapy. This condition is highly recurrent and therefore gives rise to high morbidity and mortality rates, thus entailing a vicious cycle that is difficult to solve. Percutaneous left atrial appendage closure has become a therapeutic alternative for patients with atrial fibrillation and a contraindication for oral anticoagulation. This technique would allow the discontinuation of oral anticoagulants, thus helping to reduce the risk for gastrointestinal bleeding, and would also be protective against embolic events in this group of patients, thereby eventually breaking this vicious cycle. We report our experience with percutaneous left atrial appendage closure in the management of patients with atrial fibrillation who are subject to oral anticoagulation therapy and suffer from obscure or intractable gastrointestinal bleeding.Sociedad Española de Patología DigestivaRevista Española de Enfermedades Digestivas v.106 n.5 20142014-05-01journal articletext/htmlhttp://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082014000500009en
institution SCIELO
collection OJS
country España
countrycode ES
component Revista
access En linea
databasecode rev-scielo-es
tag revista
region Europa del Sur
libraryname SciELO
language English
format Digital
author Fernández-Rodríguez,Diego
Martín-Yuste,Victoria
Feu,Faust
Brugaletta,Salvatore
Freixa,Xavier
Regueiro,Ander
Sabaté,Manel
spellingShingle Fernández-Rodríguez,Diego
Martín-Yuste,Victoria
Feu,Faust
Brugaletta,Salvatore
Freixa,Xavier
Regueiro,Ander
Sabaté,Manel
Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
author_facet Fernández-Rodríguez,Diego
Martín-Yuste,Victoria
Feu,Faust
Brugaletta,Salvatore
Freixa,Xavier
Regueiro,Ander
Sabaté,Manel
author_sort Fernández-Rodríguez,Diego
title Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
title_short Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
title_full Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
title_fullStr Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
title_full_unstemmed Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
title_sort can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy?: the role of percutaneous left atrial appendage closure
description Gastrointestinal bleeding of obscure origin or with an intractable cause is particularly common in patients with atrial fibrillation subject to oral anticoagulant therapy. This condition is highly recurrent and therefore gives rise to high morbidity and mortality rates, thus entailing a vicious cycle that is difficult to solve. Percutaneous left atrial appendage closure has become a therapeutic alternative for patients with atrial fibrillation and a contraindication for oral anticoagulation. This technique would allow the discontinuation of oral anticoagulants, thus helping to reduce the risk for gastrointestinal bleeding, and would also be protective against embolic events in this group of patients, thereby eventually breaking this vicious cycle. We report our experience with percutaneous left atrial appendage closure in the management of patients with atrial fibrillation who are subject to oral anticoagulation therapy and suffer from obscure or intractable gastrointestinal bleeding.
publisher Sociedad Española de Patología Digestiva
publishDate 2014
url http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082014000500009
work_keys_str_mv AT fernandezrodriguezdiego cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
AT martinyustevictoria cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
AT feufaust cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
AT brugalettasalvatore cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
AT freixaxavier cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
AT regueiroander cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
AT sabatemanel cantheviciouscycleofobscureorintractablegastrointestinalbleedingbebrokeninpatientswithatrialfibrillationsubjecttoanticoagulanttherapytheroleofpercutaneousleftatrialappendageclosure
_version_ 1755938666476208128