Experience with granulocytapheresis in Crohn's disease

Objective: to describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique. Conclusions: granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish “optimal patient” selection, re-treatment interval, and number of sessions.

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Bibliographic Details
Main Authors: Cuenca,F., García-Paredes,J., Mendoza,J. L., Cruz,D. M., Herrero,A., Díaz-Rubio,M.
Format: Digital revista
Language:English
Published: Sociedad Española de Patología Digestiva 2004
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082004000700007
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