Experience with granulocytapheresis in Crohn's disease

Experience with granulocytapheresis in Crohn's disease

Objective: to describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique. Conclusions: granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish “optimal patient” selection, re-treatment interval, and number of sessions.

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Main Authors: Cuenca,F., García-Paredes,J., Mendoza,J. L., Cruz,D. M., Herrero,A., Díaz-Rubio,M.
Format: Digital revista
Language:English
Published: Sociedad Española de Patología Digestiva 2004
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082004000700007
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spelling oai:scielo:S1130-010820040007000072006-08-24Experience with granulocytapheresis in Crohn's diseaseCuenca,F.García-Paredes,J.Mendoza,J. L.Cruz,D. M.Herrero,A.Díaz-Rubio,M. Granulocyte apheresis Leukocyte apheresis Ulcerative colitis Crohn's disease Inflammatory bowel disease Objective: to describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique. Conclusions: granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish “optimal patient” selection, re-treatment interval, and number of sessions.Sociedad Española de Patología DigestivaRevista Española de Enfermedades Digestivas v.96 n.7 20042004-07-01journal articletext/htmlhttp://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082004000700007en
institution SCIELO
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country España
countrycode ES
component Revista
access En linea
databasecode rev-scielo-es
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region Europa del Sur
libraryname SciELO
language English
format Digital
author Cuenca,F.
García-Paredes,J.
Mendoza,J. L.
Cruz,D. M.
Herrero,A.
Díaz-Rubio,M.
spellingShingle Cuenca,F.
García-Paredes,J.
Mendoza,J. L.
Cruz,D. M.
Herrero,A.
Díaz-Rubio,M.
Experience with granulocytapheresis in Crohn's disease
author_facet Cuenca,F.
García-Paredes,J.
Mendoza,J. L.
Cruz,D. M.
Herrero,A.
Díaz-Rubio,M.
author_sort Cuenca,F.
title Experience with granulocytapheresis in Crohn's disease
title_short Experience with granulocytapheresis in Crohn's disease
title_full Experience with granulocytapheresis in Crohn's disease
title_fullStr Experience with granulocytapheresis in Crohn's disease
title_full_unstemmed Experience with granulocytapheresis in Crohn's disease
title_sort experience with granulocytapheresis in crohn's disease
description Objective: to describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique. Conclusions: granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish “optimal patient” selection, re-treatment interval, and number of sessions.
publisher Sociedad Española de Patología Digestiva
publishDate 2004
url http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082004000700007
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AT mendozajl experiencewithgranulocytapheresisincrohnsdisease
AT cruzdm experiencewithgranulocytapheresisincrohnsdisease
AT herreroa experiencewithgranulocytapheresisincrohnsdisease
AT diazrubiom experiencewithgranulocytapheresisincrohnsdisease
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