Acute kidney injury associated with COVID-19 infection: a case report

Acute kidney injury associated with COVID-19 infection: a case report

ABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.

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Main Authors: Duarte,Tiago, Caeiro,Fernando, Góis,Mário, Matos,António, Viana,Helena, Vieira,César, Paulos,Jorge, Paixão,Paulo, Matos,Bruno, Germano,Nuno, Nolasco,Fernando
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Nefrologia 2021
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000300192
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spelling oai:scielo:S0872-016920210003001922022-01-10Acute kidney injury associated with COVID-19 infection: a case reportDuarte,TiagoCaeiro,FernandoGóis,MárioMatos,AntónioViana,HelenaVieira,CésarPaulos,JorgePaixão,PauloMatos,BrunoGermano,NunoNolasco,Fernando acute kidney injury COVID-19 kidney biopsy ABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.info:eu-repo/semantics/openAccessSociedade Portuguesa de NefrologiaPortuguese Journal of Nephrology & Hypertension v.35 n.3 20212021-09-01info:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000300192en10.32932/pjnh.2021.10.146
institution SCIELO
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country Portugal
countrycode PT
component Revista
access En linea
databasecode rev-scielo-pt
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region Europa del Sur
libraryname SciELO
language English
format Digital
author Duarte,Tiago
Caeiro,Fernando
Góis,Mário
Matos,António
Viana,Helena
Vieira,César
Paulos,Jorge
Paixão,Paulo
Matos,Bruno
Germano,Nuno
Nolasco,Fernando
spellingShingle Duarte,Tiago
Caeiro,Fernando
Góis,Mário
Matos,António
Viana,Helena
Vieira,César
Paulos,Jorge
Paixão,Paulo
Matos,Bruno
Germano,Nuno
Nolasco,Fernando
Acute kidney injury associated with COVID-19 infection: a case report
author_facet Duarte,Tiago
Caeiro,Fernando
Góis,Mário
Matos,António
Viana,Helena
Vieira,César
Paulos,Jorge
Paixão,Paulo
Matos,Bruno
Germano,Nuno
Nolasco,Fernando
author_sort Duarte,Tiago
title Acute kidney injury associated with COVID-19 infection: a case report
title_short Acute kidney injury associated with COVID-19 infection: a case report
title_full Acute kidney injury associated with COVID-19 infection: a case report
title_fullStr Acute kidney injury associated with COVID-19 infection: a case report
title_full_unstemmed Acute kidney injury associated with COVID-19 infection: a case report
title_sort acute kidney injury associated with covid-19 infection: a case report
description ABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.
publisher Sociedade Portuguesa de Nefrologia
publishDate 2021
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000300192
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