Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report

Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report

We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.

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Main Authors: Jafry,Nazrul Hassan, Mubarak,Muhammad, Anis,Sabiha, Ahmed,Ejaz, Akhtar,Fazal
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Nefrologia 2019
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009
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spelling oai:scielo:S0872-016920190002000092019-09-04Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case reportJafry,Nazrul HassanMubarak,MuhammadAnis,SabihaAhmed,EjazAkhtar,Fazal Myeloma casts acute tubular injury HIV anti-retroviral therapy We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.info:eu-repo/semantics/openAccessSociedade Portuguesa de NefrologiaPortuguese Journal of Nephrology & Hypertension v.33 n.2 20192019-06-01info:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009en10.32932/pjnh.2019.07.024
institution SCIELO
collection OJS
country Portugal
countrycode PT
component Revista
access En linea
databasecode rev-scielo-pt
tag revista
region Europa del Sur
libraryname SciELO
language English
format Digital
author Jafry,Nazrul Hassan
Mubarak,Muhammad
Anis,Sabiha
Ahmed,Ejaz
Akhtar,Fazal
spellingShingle Jafry,Nazrul Hassan
Mubarak,Muhammad
Anis,Sabiha
Ahmed,Ejaz
Akhtar,Fazal
Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
author_facet Jafry,Nazrul Hassan
Mubarak,Muhammad
Anis,Sabiha
Ahmed,Ejaz
Akhtar,Fazal
author_sort Jafry,Nazrul Hassan
title Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_short Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_full Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_fullStr Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_full_unstemmed Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_sort myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
description We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.
publisher Sociedade Portuguesa de Nefrologia
publishDate 2019
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009
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AT mubarakmuhammad myelomalikecastnephropathyinahumanimmunodeficiencyvirusinfectedpatientacasereport
AT anissabiha myelomalikecastnephropathyinahumanimmunodeficiencyvirusinfectedpatientacasereport
AT ahmedejaz myelomalikecastnephropathyinahumanimmunodeficiencyvirusinfectedpatientacasereport
AT akhtarfazal myelomalikecastnephropathyinahumanimmunodeficiencyvirusinfectedpatientacasereport
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