The first ABO-incompatible kidney transplantation performed in Portugal

Kidney transplantation is the optimal treatment of end -stage renal disease (ESRD) improving survival and quality of life for most recipients. In our country, potential living donors have been refused due to the ABO incompatibility barrier. However, ABO -incompatible living donor kidney transplant is presently common practice in several countries with good outcomes. The authors describe a case of a 49 -year -old female patient, with chronic kidney disease due to autosomal dominant polycystic kidney disease, who had started haemodialysis 10 months before and with blood group O. The living donor was a 53-year-old sister with blood group B. The desensitization protocol was based on rituximab and plasmapheresis. The induction protocol used was basiliximab, tacrolimus, mofetil mycophenolate and metilprednisolone. Five days post -transplant she presented a normal graft function that remained during the eight months follow -up. This case reveals the first ABO incompatible living donor kidney transplant performed in Portugal with excellent outcome

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Main Authors: Barreto,Patricia, Vieira,Pedro, Dias,Leonidio, Almeida,Manuela, Pedroso,Sofia, Martins,La Salete, Henriques,Antonio Castro, Bini,Marika, Cabrita,Antonio
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Nefrologia 2015
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692015000400009
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spelling oai:scielo:S0872-016920150004000092016-02-03The first ABO-incompatible kidney transplantation performed in PortugalBarreto,PatriciaVieira,PedroDias,LeonidioAlmeida,ManuelaPedroso,SofiaMartins,La SaleteHenriques,Antonio CastroBini,MarikaCabrita,Antonio ABO-incompatibility kidney transplantation living donor Kidney transplantation is the optimal treatment of end -stage renal disease (ESRD) improving survival and quality of life for most recipients. In our country, potential living donors have been refused due to the ABO incompatibility barrier. However, ABO -incompatible living donor kidney transplant is presently common practice in several countries with good outcomes. The authors describe a case of a 49 -year -old female patient, with chronic kidney disease due to autosomal dominant polycystic kidney disease, who had started haemodialysis 10 months before and with blood group O. The living donor was a 53-year-old sister with blood group B. The desensitization protocol was based on rituximab and plasmapheresis. The induction protocol used was basiliximab, tacrolimus, mofetil mycophenolate and metilprednisolone. Five days post -transplant she presented a normal graft function that remained during the eight months follow -up. This case reveals the first ABO incompatible living donor kidney transplant performed in Portugal with excellent outcomeinfo:eu-repo/semantics/openAccessSociedade Portuguesa de NefrologiaPortuguese Journal of Nephrology & Hypertension v.29 n.4 20152015-12-01info:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692015000400009en
institution SCIELO
collection OJS
country Portugal
countrycode PT
component Revista
access En linea
databasecode rev-scielo-pt
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region Europa del Sur
libraryname SciELO
language English
format Digital
author Barreto,Patricia
Vieira,Pedro
Dias,Leonidio
Almeida,Manuela
Pedroso,Sofia
Martins,La Salete
Henriques,Antonio Castro
Bini,Marika
Cabrita,Antonio
spellingShingle Barreto,Patricia
Vieira,Pedro
Dias,Leonidio
Almeida,Manuela
Pedroso,Sofia
Martins,La Salete
Henriques,Antonio Castro
Bini,Marika
Cabrita,Antonio
The first ABO-incompatible kidney transplantation performed in Portugal
author_facet Barreto,Patricia
Vieira,Pedro
Dias,Leonidio
Almeida,Manuela
Pedroso,Sofia
Martins,La Salete
Henriques,Antonio Castro
Bini,Marika
Cabrita,Antonio
author_sort Barreto,Patricia
title The first ABO-incompatible kidney transplantation performed in Portugal
title_short The first ABO-incompatible kidney transplantation performed in Portugal
title_full The first ABO-incompatible kidney transplantation performed in Portugal
title_fullStr The first ABO-incompatible kidney transplantation performed in Portugal
title_full_unstemmed The first ABO-incompatible kidney transplantation performed in Portugal
title_sort first abo-incompatible kidney transplantation performed in portugal
description Kidney transplantation is the optimal treatment of end -stage renal disease (ESRD) improving survival and quality of life for most recipients. In our country, potential living donors have been refused due to the ABO incompatibility barrier. However, ABO -incompatible living donor kidney transplant is presently common practice in several countries with good outcomes. The authors describe a case of a 49 -year -old female patient, with chronic kidney disease due to autosomal dominant polycystic kidney disease, who had started haemodialysis 10 months before and with blood group O. The living donor was a 53-year-old sister with blood group B. The desensitization protocol was based on rituximab and plasmapheresis. The induction protocol used was basiliximab, tacrolimus, mofetil mycophenolate and metilprednisolone. Five days post -transplant she presented a normal graft function that remained during the eight months follow -up. This case reveals the first ABO incompatible living donor kidney transplant performed in Portugal with excellent outcome
publisher Sociedade Portuguesa de Nefrologia
publishDate 2015
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692015000400009
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