Primary glomerular diseases: variations in disease types seen in Africa and Europe

Primary glomerular diseases: variations in disease types seen in Africa and Europe

Glomerular diseases account for a significant number of patients with chronic kidney disease worldwide. IgA nephropathy (IgAN) is the predominant primary glomerular disease (PGD) seen across Europe, whereas in Africa, the prevalence of IgAN is not common. The most frequently described glomerular disease in Africa is mesangiocapillary glomerulonephritis (MCGN). The difference in the prevalence of PGDs seen in Africa and Europe may depend on several factors including genetic, socio-economic and demographic influences. Variations in exposure to infections (hygiene hypothesis) and patterns of Th1 and Th2 responses may also contribute significantly to observed differences.

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Main Authors: Okpechi,Ikechi, Duffield,Maureen, Swanepoel,Charles
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Nefrologia 2012
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692012000100003
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spelling oai:scielo:S0872-016920120001000032020-05-28Primary glomerular diseases: variations in disease types seen in Africa and EuropeOkpechi,IkechiDuffield,MaureenSwanepoel,Charles Glomerulonephritis in Africa Glomerulonephritis in Europe Primary glomerulonephritis Glomerular diseases account for a significant number of patients with chronic kidney disease worldwide. IgA nephropathy (IgAN) is the predominant primary glomerular disease (PGD) seen across Europe, whereas in Africa, the prevalence of IgAN is not common. The most frequently described glomerular disease in Africa is mesangiocapillary glomerulonephritis (MCGN). The difference in the prevalence of PGDs seen in Africa and Europe may depend on several factors including genetic, socio-economic and demographic influences. Variations in exposure to infections (hygiene hypothesis) and patterns of Th1 and Th2 responses may also contribute significantly to observed differences.info:eu-repo/semantics/openAccessSociedade Portuguesa de NefrologiaPortuguese Journal of Nephrology & Hypertension v.26 n.1 20122012-01-01info:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692012000100003en
institution SCIELO
collection OJS
country Portugal
countrycode PT
component Revista
access En linea
databasecode rev-scielo-pt
tag revista
region Europa del Sur
libraryname SciELO
language English
format Digital
author Okpechi,Ikechi
Duffield,Maureen
Swanepoel,Charles
spellingShingle Okpechi,Ikechi
Duffield,Maureen
Swanepoel,Charles
Primary glomerular diseases: variations in disease types seen in Africa and Europe
author_facet Okpechi,Ikechi
Duffield,Maureen
Swanepoel,Charles
author_sort Okpechi,Ikechi
title Primary glomerular diseases: variations in disease types seen in Africa and Europe
title_short Primary glomerular diseases: variations in disease types seen in Africa and Europe
title_full Primary glomerular diseases: variations in disease types seen in Africa and Europe
title_fullStr Primary glomerular diseases: variations in disease types seen in Africa and Europe
title_full_unstemmed Primary glomerular diseases: variations in disease types seen in Africa and Europe
title_sort primary glomerular diseases: variations in disease types seen in africa and europe
description Glomerular diseases account for a significant number of patients with chronic kidney disease worldwide. IgA nephropathy (IgAN) is the predominant primary glomerular disease (PGD) seen across Europe, whereas in Africa, the prevalence of IgAN is not common. The most frequently described glomerular disease in Africa is mesangiocapillary glomerulonephritis (MCGN). The difference in the prevalence of PGDs seen in Africa and Europe may depend on several factors including genetic, socio-economic and demographic influences. Variations in exposure to infections (hygiene hypothesis) and patterns of Th1 and Th2 responses may also contribute significantly to observed differences.
publisher Sociedade Portuguesa de Nefrologia
publishDate 2012
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692012000100003
work_keys_str_mv AT okpechiikechi primaryglomerulardiseasesvariationsindiseasetypesseeninafricaandeurope
AT duffieldmaureen primaryglomerulardiseasesvariationsindiseasetypesseeninafricaandeurope
AT swanepoelcharles primaryglomerulardiseasesvariationsindiseasetypesseeninafricaandeurope
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