Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats

SUMMARY: Peripheral nerve damage is a significant clinical problem that can lead to severe complications in patients. Regarding the regeneration of peripheral nerves, it is crucial to use experimental animals' nerves and use different evaluation methods. Epineural or perineural suturing is the gold standard in treating sciatic nerve injury, but nerve repair is often unsuccessful. This study aimed to investigate the neuroregenerative effects of magnetotherapy and bioresonance in experimental animals with sciatic nerve damage. In this study, 24 female Wistar rats were divided into 7 groups (n=6) as follows: Group 1 (Control), Group 2 (Axonotmesis control), Group 3 (Anastomosis control), Group 4 (Axonotmesis + magnetotherapy), Group 5 (Anastomosis + magnetotherapy), Group 6 (Axonotmesis + bioresonance), Group 7 (Anastomosis + bioresonance). Magnetotherapy and bioresonance treatments were applied for 12 weeks. Behavioural tests and EMG tests were performed at the end of the 12th week. Then the rats were sacrificed, and a histopathological evaluation was made. The statistical significance level was taken as 5 % in the calculations, and the SPSS (IBM SPSS for Windows, ver.21) statistical package program was used for the calculations. Statistically significant results were obtained in animal behaviour tests, EMG, and pathology groups treated with magnetotherapy. There was no statistically significant difference in the groups treated with bioresonance treatment compared to the control groups. Muscle activity and nerve repair occurred in experimental animals with acute peripheral nerve damage due to 12 weeks of magnetotherapy, and further studies should support these results.

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Main Authors: Tas,Abdurrahim, Nalci,Kemal Alp, Sincan,Suat, Özdemir,Hülya, Üstün,Ramazan, Aras,I˙brahim, Çatalkaya,Ege, Seker,Ayse, Aycan,Abdurrahman, Aycan,Nur, Gürsoy,Görkem Tutal, Tuncer,Mehmet Cudi
Format: Digital revista
Language:English
Published: Sociedad Chilena de Anatomía 2023
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022023000401184
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spelling oai:scielo:S0717-950220230004011842023-09-27Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced RatsTas,AbdurrahimNalci,Kemal AlpSincan,SuatÖzdemir,HülyaÜstün,RamazanAras,I˙brahimÇatalkaya,EgeSeker,AyseAycan,AbdurrahmanAycan,NurGürsoy,Görkem TutalTuncer,Mehmet Cudi Bioresonance EMG Magnetotheraphy Nerve regeneration Sciatic nerve SUMMARY: Peripheral nerve damage is a significant clinical problem that can lead to severe complications in patients. Regarding the regeneration of peripheral nerves, it is crucial to use experimental animals' nerves and use different evaluation methods. Epineural or perineural suturing is the gold standard in treating sciatic nerve injury, but nerve repair is often unsuccessful. This study aimed to investigate the neuroregenerative effects of magnetotherapy and bioresonance in experimental animals with sciatic nerve damage. In this study, 24 female Wistar rats were divided into 7 groups (n=6) as follows: Group 1 (Control), Group 2 (Axonotmesis control), Group 3 (Anastomosis control), Group 4 (Axonotmesis + magnetotherapy), Group 5 (Anastomosis + magnetotherapy), Group 6 (Axonotmesis + bioresonance), Group 7 (Anastomosis + bioresonance). Magnetotherapy and bioresonance treatments were applied for 12 weeks. Behavioural tests and EMG tests were performed at the end of the 12th week. Then the rats were sacrificed, and a histopathological evaluation was made. The statistical significance level was taken as 5 % in the calculations, and the SPSS (IBM SPSS for Windows, ver.21) statistical package program was used for the calculations. Statistically significant results were obtained in animal behaviour tests, EMG, and pathology groups treated with magnetotherapy. There was no statistically significant difference in the groups treated with bioresonance treatment compared to the control groups. Muscle activity and nerve repair occurred in experimental animals with acute peripheral nerve damage due to 12 weeks of magnetotherapy, and further studies should support these results.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.41 n.4 20232023-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022023000401184en10.4067/S0717-95022023000401184
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libraryname SciELO
language English
format Digital
author Tas,Abdurrahim
Nalci,Kemal Alp
Sincan,Suat
Özdemir,Hülya
Üstün,Ramazan
Aras,I˙brahim
Çatalkaya,Ege
Seker,Ayse
Aycan,Abdurrahman
Aycan,Nur
Gürsoy,Görkem Tutal
Tuncer,Mehmet Cudi
spellingShingle Tas,Abdurrahim
Nalci,Kemal Alp
Sincan,Suat
Özdemir,Hülya
Üstün,Ramazan
Aras,I˙brahim
Çatalkaya,Ege
Seker,Ayse
Aycan,Abdurrahman
Aycan,Nur
Gürsoy,Görkem Tutal
Tuncer,Mehmet Cudi
Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats
author_facet Tas,Abdurrahim
Nalci,Kemal Alp
Sincan,Suat
Özdemir,Hülya
Üstün,Ramazan
Aras,I˙brahim
Çatalkaya,Ege
Seker,Ayse
Aycan,Abdurrahman
Aycan,Nur
Gürsoy,Görkem Tutal
Tuncer,Mehmet Cudi
author_sort Tas,Abdurrahim
title Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats
title_short Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats
title_full Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats
title_fullStr Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats
title_full_unstemmed Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats
title_sort investigation of the neuro-regenerative effects of bioresonance and magnetotherapy in sciatic nerve damage-induced rats
description SUMMARY: Peripheral nerve damage is a significant clinical problem that can lead to severe complications in patients. Regarding the regeneration of peripheral nerves, it is crucial to use experimental animals' nerves and use different evaluation methods. Epineural or perineural suturing is the gold standard in treating sciatic nerve injury, but nerve repair is often unsuccessful. This study aimed to investigate the neuroregenerative effects of magnetotherapy and bioresonance in experimental animals with sciatic nerve damage. In this study, 24 female Wistar rats were divided into 7 groups (n=6) as follows: Group 1 (Control), Group 2 (Axonotmesis control), Group 3 (Anastomosis control), Group 4 (Axonotmesis + magnetotherapy), Group 5 (Anastomosis + magnetotherapy), Group 6 (Axonotmesis + bioresonance), Group 7 (Anastomosis + bioresonance). Magnetotherapy and bioresonance treatments were applied for 12 weeks. Behavioural tests and EMG tests were performed at the end of the 12th week. Then the rats were sacrificed, and a histopathological evaluation was made. The statistical significance level was taken as 5 % in the calculations, and the SPSS (IBM SPSS for Windows, ver.21) statistical package program was used for the calculations. Statistically significant results were obtained in animal behaviour tests, EMG, and pathology groups treated with magnetotherapy. There was no statistically significant difference in the groups treated with bioresonance treatment compared to the control groups. Muscle activity and nerve repair occurred in experimental animals with acute peripheral nerve damage due to 12 weeks of magnetotherapy, and further studies should support these results.
publisher Sociedad Chilena de Anatomía
publishDate 2023
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022023000401184
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