Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases

The association among clinicopathological features and c-erbB-2 oncoprotein expression was evaluated in twenty-nine cases of intra-oral mucoepidermoid carcinoma (MEC). MEC was prevalent in the female gender (79.3%), tumors were more frequent in ages between 21 and 40 years (48.3%), and the palate was the most commonly affected site (72.4%). Microscopically, 27 cases (93.1%) were classified as low grade of malignancy. The c-erbB-2 expression was considered positive in 9 (31%) cases and no significant association (p>0.05) was found among protein expression and gender ñor between patient age and site or histological grade of the lesión. c-erbB-2 expression in MEC may reflect intrisinc biologic properties of salivary gland neoplasms and may be linked to histogenesis and cellular differentiaton.

Bibliographic Details

Main Authors:	Bernardes,Vanessa Fátima, Ramos-Jorge,Maria Letícia, Vieira Carmo,Maria Auxiliadora, Cardoso,Sérgio Vitorino, Alves Mesquita,Ricardo, Ferreira Aguiar,Maria Cássia
Format:	Digital revista
Language:	English
Published:	Sociedad Chilena de Anatomía 2008
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400036
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