Atherogenic index of plasma is reduced during follow-up among Roux-in-Y gastric bypass patients

ABSTRACT Atherogenic index of plasma is a marker used to assess risk of cardiovascular diseases. The present study evaluated plasma atherogenic index in individuals before and after bariatric surgery. Individuals were evaluated at three time points: before surgery (T0), in the 2nd (T1) and 6th (T2) months post-surgery. Anthropometric (body mass index, waist circumference, fat and lean mass) and biochemical parameters (lipid profile, glucose and C-reactive protein), and atherogenic index of plasma, calculated by the formula [=log (serum triglycerides concentration/HDL cholesterol)], were evaluated. Data were analyzed using the repeated measures ANOVA or Friedman test according to data distribution. The level of significance was 5%. Thirty-four patients agreed to participate. A significant reduction was observed in all anthropometric parameters in women and men (p<0.05). Atherogenic index of plasma reduced significantly in all time points in women; there was a significant reduction only between periods T0 and T2 (p<0.05) in men. A reduction in the classification for risk in cardiovascular diseases, with high risk in T0 (0.441±0.13) to moderate risk at T1 (0.204±0.22) and low risk at T2 (0.041±0.16) was observed in men. In women, the risk remained low (<0.11) in all periods. Bariatric surgery reduced the atherogenic index of plasma during the 6-month follow-up, suggesting a reduction in cardiovascular risk.

Bibliographic Details

Main Authors:	Teixeira-Gomes,Patricia Helena, Moraes,Rafael Araújo Guedes de, Soares-Miguel,Gustavo Peixoto, Graça-Pedrosa,Rogerio, Haraguchi,Fabiano Kenji
Format:	Digital revista
Language:	English
Published:	Sociedad Chilena de Nutrición, Bromatología y Toxicología 2021
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182021000500768
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