ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE

ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE

The present work aims at establishing the toxic effects on spermatogenesis of a single injection of the organophosphorous agropesticide Parathion, administered to immature male mice. Seven days old animals were injected intraperitoneally with 1/3 the LD50. Body and testicular weights were measured. Quantitative as well as qualitative analysis of seminiferous tubules and germ cell populations were done for control and injected mice 8, 16, 28 and 50 days after injection. The cytotoxic effect of the pesticide is substantiated by a decrease of body and testis weight and an early damage of germ cells in treated mice. The effect is reversible and recovers at longer intervals

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Main Authors: Sobarzo,Cristián, Bustos-Obregón,Eduardo
Format: Digital revista
Language:English
Published: Sociedad Chilena de Anatomía 2000
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-98682000000100008
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spelling oai:scielo:S0716-986820000001000082005-10-04ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICESobarzo,CristiánBustos-Obregón,Eduardo Agropesticides Spermatogenic Mice The present work aims at establishing the toxic effects on spermatogenesis of a single injection of the organophosphorous agropesticide Parathion, administered to immature male mice. Seven days old animals were injected intraperitoneally with 1/3 the LD50. Body and testicular weights were measured. Quantitative as well as qualitative analysis of seminiferous tubules and germ cell populations were done for control and injected mice 8, 16, 28 and 50 days after injection. The cytotoxic effect of the pesticide is substantiated by a decrease of body and testis weight and an early damage of germ cells in treated mice. The effect is reversible and recovers at longer intervalsinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaRevista chilena de anatomía v.18 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-98682000000100008en10.4067/S0716-98682000000100008
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Sobarzo,Cristián
Bustos-Obregón,Eduardo
spellingShingle Sobarzo,Cristián
Bustos-Obregón,Eduardo
ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
author_facet Sobarzo,Cristián
Bustos-Obregón,Eduardo
author_sort Sobarzo,Cristián
title ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_short ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_full ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_fullStr ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_full_unstemmed ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_sort acute effect of parathion on the seminiferous epithelium of immature mice
description The present work aims at establishing the toxic effects on spermatogenesis of a single injection of the organophosphorous agropesticide Parathion, administered to immature male mice. Seven days old animals were injected intraperitoneally with 1/3 the LD50. Body and testicular weights were measured. Quantitative as well as qualitative analysis of seminiferous tubules and germ cell populations were done for control and injected mice 8, 16, 28 and 50 days after injection. The cytotoxic effect of the pesticide is substantiated by a decrease of body and testis weight and an early damage of germ cells in treated mice. The effect is reversible and recovers at longer intervals
publisher Sociedad Chilena de Anatomía
publishDate 2000
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-98682000000100008
work_keys_str_mv AT sobarzocristian acuteeffectofparathionontheseminiferousepitheliumofimmaturemice
AT bustosobregoneduardo acuteeffectofparathionontheseminiferousepitheliumofimmaturemice
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