A simple and efficient synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-ones by ZnO nanoparticles catalyzed three component coupling reaction of aldehydes, 2-naphthol and dimedone
Highly effective zinc oxide nanoparticles catalyzed solvent-free synthesis of some tetrahydrobenzo[a]xanthen-11-one derivatives via one-pot multi-component reaction of aldehydes, 2-naphthol and dimedone. The present approach creates a variety of biologically active heterocyclic compounds in excellent yields and short reaction times. Four new compounds are reported. The salient features of the ZnO nanoparticles are: easy preparation, cost-effective, high stability, low loading and reusability of the catalyst. The prepared zinc oxide nanoparticles were fully characterized by EDX, XRD, SEM, IR and TEM analysis.
Main Authors: | , |
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Format: | Digital revista |
Language: | English |
Published: |
The South African Chemical Institute
2014
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Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502014000100005 |
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Summary: | Highly effective zinc oxide nanoparticles catalyzed solvent-free synthesis of some tetrahydrobenzo[a]xanthen-11-one derivatives via one-pot multi-component reaction of aldehydes, 2-naphthol and dimedone. The present approach creates a variety of biologically active heterocyclic compounds in excellent yields and short reaction times. Four new compounds are reported. The salient features of the ZnO nanoparticles are: easy preparation, cost-effective, high stability, low loading and reusability of the catalyst. The prepared zinc oxide nanoparticles were fully characterized by EDX, XRD, SEM, IR and TEM analysis. |
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