Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response
Abstract Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a disseminated papulo-vesiculous eruption, diagnosed as varicella. Few days after recovering, an erythematous and violaceous papular dermatosis with histopathological examination compatible with leukemic infiltration appeared on the scars of previous herpetic lesions. Complete remission was obtained under systemic corticotherapy, without cutaneous recurrence or blastic transformation. Wolf's isotopic response is attributed to a localized immunologic imbalance following a certain stimulus. In this patient, herpetic infection acted as a local spur for inaugural cutaneous leukemic infiltration, with no impact on the prognosis for the underlying disease.
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Sociedade Brasileira de Dermatologia
2016
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oai:scielo:S0365-059620160011000722017-03-03Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic responseBrasileiro,AnaLencastre,AndréJoão,AlexandreFidalgo,Ana Chickenpox Leukemic infiltration Leukemia, lymphocytic, chronic, B-cell Abstract Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a disseminated papulo-vesiculous eruption, diagnosed as varicella. Few days after recovering, an erythematous and violaceous papular dermatosis with histopathological examination compatible with leukemic infiltration appeared on the scars of previous herpetic lesions. Complete remission was obtained under systemic corticotherapy, without cutaneous recurrence or blastic transformation. Wolf's isotopic response is attributed to a localized immunologic imbalance following a certain stimulus. In this patient, herpetic infection acted as a local spur for inaugural cutaneous leukemic infiltration, with no impact on the prognosis for the underlying disease.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.91 n.5 suppl.1 20162016-10-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100072en10.1590/abd1806-4841.20164686 |
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Brasileiro,Ana Lencastre,André João,Alexandre Fidalgo,Ana |
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Brasileiro,Ana Lencastre,André João,Alexandre Fidalgo,Ana Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
| author_facet |
Brasileiro,Ana Lencastre,André João,Alexandre Fidalgo,Ana |
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Brasileiro,Ana |
| title |
Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
| title_short |
Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
| title_full |
Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
| title_fullStr |
Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
| title_full_unstemmed |
Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
| title_sort |
cutaneous leukemic infiltration following varicella - a case of wolf's isotopic response |
| description |
Abstract Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a disseminated papulo-vesiculous eruption, diagnosed as varicella. Few days after recovering, an erythematous and violaceous papular dermatosis with histopathological examination compatible with leukemic infiltration appeared on the scars of previous herpetic lesions. Complete remission was obtained under systemic corticotherapy, without cutaneous recurrence or blastic transformation. Wolf's isotopic response is attributed to a localized immunologic imbalance following a certain stimulus. In this patient, herpetic infection acted as a local spur for inaugural cutaneous leukemic infiltration, with no impact on the prognosis for the underlying disease. |
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Sociedade Brasileira de Dermatologia |
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2016 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100072 |
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1756412551196835840 |