Diffuse neurofibroma - an uncommon cause of alopecia

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.

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Main Authors: Macias,Vasco Coelho, Rafael,Margarida, Fernandes,Cândida, Rosa,Joaninha Costa
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800166
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spelling oai:scielo:S0365-059620130008001662014-06-16Diffuse neurofibroma - an uncommon cause of alopeciaMacias,Vasco CoelhoRafael,MargaridaFernandes,CândidaRosa,Joaninha Costa Alopecia Neurofibroma Scalp Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.88 n.6 suppl.1 20132013-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800166en10.1590/abd1806-4841.20132170
institution SCIELO
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Macias,Vasco Coelho
Rafael,Margarida
Fernandes,Cândida
Rosa,Joaninha Costa
spellingShingle Macias,Vasco Coelho
Rafael,Margarida
Fernandes,Cândida
Rosa,Joaninha Costa
Diffuse neurofibroma - an uncommon cause of alopecia
author_facet Macias,Vasco Coelho
Rafael,Margarida
Fernandes,Cândida
Rosa,Joaninha Costa
author_sort Macias,Vasco Coelho
title Diffuse neurofibroma - an uncommon cause of alopecia
title_short Diffuse neurofibroma - an uncommon cause of alopecia
title_full Diffuse neurofibroma - an uncommon cause of alopecia
title_fullStr Diffuse neurofibroma - an uncommon cause of alopecia
title_full_unstemmed Diffuse neurofibroma - an uncommon cause of alopecia
title_sort diffuse neurofibroma - an uncommon cause of alopecia
description Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.
publisher Sociedade Brasileira de Dermatologia
publishDate 2013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800166
work_keys_str_mv AT maciasvascocoelho diffuseneurofibromaanuncommoncauseofalopecia
AT rafaelmargarida diffuseneurofibromaanuncommoncauseofalopecia
AT fernandescandida diffuseneurofibromaanuncommoncauseofalopecia
AT rosajoaninhacosta diffuseneurofibromaanuncommoncauseofalopecia
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