Diffuse neurofibroma - an uncommon cause of alopecia
Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.
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Sociedade Brasileira de Dermatologia
2013
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oai:scielo:S0365-059620130008001662014-06-16Diffuse neurofibroma - an uncommon cause of alopeciaMacias,Vasco CoelhoRafael,MargaridaFernandes,CândidaRosa,Joaninha Costa Alopecia Neurofibroma Scalp Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.88 n.6 suppl.1 20132013-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800166en10.1590/abd1806-4841.20132170 |
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Macias,Vasco Coelho Rafael,Margarida Fernandes,Cândida Rosa,Joaninha Costa |
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Macias,Vasco Coelho Rafael,Margarida Fernandes,Cândida Rosa,Joaninha Costa Diffuse neurofibroma - an uncommon cause of alopecia |
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Macias,Vasco Coelho Rafael,Margarida Fernandes,Cândida Rosa,Joaninha Costa |
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Macias,Vasco Coelho |
title |
Diffuse neurofibroma - an uncommon cause of alopecia |
title_short |
Diffuse neurofibroma - an uncommon cause of alopecia |
title_full |
Diffuse neurofibroma - an uncommon cause of alopecia |
title_fullStr |
Diffuse neurofibroma - an uncommon cause of alopecia |
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Diffuse neurofibroma - an uncommon cause of alopecia |
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diffuse neurofibroma - an uncommon cause of alopecia |
description |
Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques. |
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Sociedade Brasileira de Dermatologia |
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2013 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800166 |
work_keys_str_mv |
AT maciasvascocoelho diffuseneurofibromaanuncommoncauseofalopecia AT rafaelmargarida diffuseneurofibromaanuncommoncauseofalopecia AT fernandescandida diffuseneurofibromaanuncommoncauseofalopecia AT rosajoaninhacosta diffuseneurofibromaanuncommoncauseofalopecia |
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