Endogenous heparin levels in the controlled asthmatic patient

Endogenous heparin levels in the controlled asthmatic patient

BACKGROUND: Since heparin possesses anti-inflammatory properties, it is hypothesised that asthmatic patients have decreased levels of circulating heparin compared with healthy individuals. DESIGN: We compared endogenous heparin levels in controlled asthmatic patients (53 adults) from the Asthma Clinic at Johannesburg General Hospital with those of healthy controls (26 adults) from the general population. Heparin levels in the blood samples were tested using the Chromogenix Coatest Heparin kit. RESULT: The blood of the patients contained significantly lower levels of endogenous heparin compared with that of the healthy individuals, indicating that the anti-inflammatory properties afforded by heparin are absent in these patients.

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Main Authors: Davids,Hajierah, Ahmed,Ayesha, Oberholster,Ari, Westhuizen,Christo van der, Mer,Mervyn, Havlik,Ivan
Format: Digital revista
Language:English
Published: South African Medical Association 2010
Online Access:http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742010000500020
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spelling oai:scielo:S0256-957420100005000202010-07-06Endogenous heparin levels in the controlled asthmatic patientDavids,HajierahAhmed,AyeshaOberholster,AriWesthuizen,Christo van derMer,MervynHavlik,IvanBACKGROUND: Since heparin possesses anti-inflammatory properties, it is hypothesised that asthmatic patients have decreased levels of circulating heparin compared with healthy individuals. DESIGN: We compared endogenous heparin levels in controlled asthmatic patients (53 adults) from the Asthma Clinic at Johannesburg General Hospital with those of healthy controls (26 adults) from the general population. Heparin levels in the blood samples were tested using the Chromogenix Coatest Heparin kit. RESULT: The blood of the patients contained significantly lower levels of endogenous heparin compared with that of the healthy individuals, indicating that the anti-inflammatory properties afforded by heparin are absent in these patients.South African Medical AssociationSAMJ: South African Medical Journal v.100 n.5 20102010-05-01journal articletext/htmlhttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742010000500020en
institution SCIELO
collection OJS
country Sudáfrica
countrycode ZA
component Revista
access En linea
databasecode rev-scielo-za
tag revista
region África del Sur
libraryname SciELO
language English
format Digital
author Davids,Hajierah
Ahmed,Ayesha
Oberholster,Ari
Westhuizen,Christo van der
Mer,Mervyn
Havlik,Ivan
spellingShingle Davids,Hajierah
Ahmed,Ayesha
Oberholster,Ari
Westhuizen,Christo van der
Mer,Mervyn
Havlik,Ivan
Endogenous heparin levels in the controlled asthmatic patient
author_facet Davids,Hajierah
Ahmed,Ayesha
Oberholster,Ari
Westhuizen,Christo van der
Mer,Mervyn
Havlik,Ivan
author_sort Davids,Hajierah
title Endogenous heparin levels in the controlled asthmatic patient
title_short Endogenous heparin levels in the controlled asthmatic patient
title_full Endogenous heparin levels in the controlled asthmatic patient
title_fullStr Endogenous heparin levels in the controlled asthmatic patient
title_full_unstemmed Endogenous heparin levels in the controlled asthmatic patient
title_sort endogenous heparin levels in the controlled asthmatic patient
description BACKGROUND: Since heparin possesses anti-inflammatory properties, it is hypothesised that asthmatic patients have decreased levels of circulating heparin compared with healthy individuals. DESIGN: We compared endogenous heparin levels in controlled asthmatic patients (53 adults) from the Asthma Clinic at Johannesburg General Hospital with those of healthy controls (26 adults) from the general population. Heparin levels in the blood samples were tested using the Chromogenix Coatest Heparin kit. RESULT: The blood of the patients contained significantly lower levels of endogenous heparin compared with that of the healthy individuals, indicating that the anti-inflammatory properties afforded by heparin are absent in these patients.
publisher South African Medical Association
publishDate 2010
url http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742010000500020
work_keys_str_mv AT davidshajierah endogenousheparinlevelsinthecontrolledasthmaticpatient
AT ahmedayesha endogenousheparinlevelsinthecontrolledasthmaticpatient
AT oberholsterari endogenousheparinlevelsinthecontrolledasthmaticpatient
AT westhuizenchristovander endogenousheparinlevelsinthecontrolledasthmaticpatient
AT mermervyn endogenousheparinlevelsinthecontrolledasthmaticpatient
AT havlikivan endogenousheparinlevelsinthecontrolledasthmaticpatient
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