Metabolic syndrome components can predict C reactive protein concentration in adolescents
Background: Metabolic syndrome (MS) is suggested to be associated with a low grade inflammation state, but the relationship between inflammation biomarkers and the components of metabolic syndrome in adolescents are still lacking. Objective: To investigate the association between C-reactive protein (CRP) serum concentrations and metabolic syndrome components in adolescents. Methods: A cross-sectional population based study was conducted. Anthropometric, biochemical and clinical data were collected from 524 adolescents (11-15 years old) randomly sampled from school population of Alegre city, Espmto Santo, Brazil. Data were analyzed by STATA version 9.0. Results: Adolescents with higher values for BMI (p = 0.001) and higher body fat percentage (p = 0.003) had higher CRP concentrations than those with lower BMI and body fat percentage. CRP concentrations was directly correlated with BMI (r = 0.17, p = 0.0001), waist circumference (r = 0.15, p = 0.0005), HDL-c (r = 0.13, p = 0.003), fasting insulin (r = 0.12, p = 0.003) and systolic blood pressure (r = 0.11, p with = 0.01). In the multiple linear regression analysis BMI (r = 0.05, p = 0.002), fasting glucose (r = -0.01, p = 0.003) and HDL-c (r = 0.017, p < 0.001) were associated to CRP concentrations after adjusting for the other components of MS. Conclusion: The association found between individual components of MS and CRP concentrations suggests that inflammation might be an early event in the development of metabolic disorders in adolescents.
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Grupo Arán
2013
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oai:scielo:S0212-161120130005000322014-11-05Metabolic syndrome components can predict C reactive protein concentration in adolescentsLeandro da Cruz,LarissaCardoso,Luciane DanielePala,DanielaPaula,Heberth deAlves Lamounier,JoelMariano Silva,Camilo AdaltonPinheiro Volp,Ana CarolinaNascimento de Freitas,Renata Adolescents Risk factors C reactive protein Metabolic syndrome x Obesity Background: Metabolic syndrome (MS) is suggested to be associated with a low grade inflammation state, but the relationship between inflammation biomarkers and the components of metabolic syndrome in adolescents are still lacking. Objective: To investigate the association between C-reactive protein (CRP) serum concentrations and metabolic syndrome components in adolescents. Methods: A cross-sectional population based study was conducted. Anthropometric, biochemical and clinical data were collected from 524 adolescents (11-15 years old) randomly sampled from school population of Alegre city, Espmto Santo, Brazil. Data were analyzed by STATA version 9.0. Results: Adolescents with higher values for BMI (p = 0.001) and higher body fat percentage (p = 0.003) had higher CRP concentrations than those with lower BMI and body fat percentage. CRP concentrations was directly correlated with BMI (r = 0.17, p = 0.0001), waist circumference (r = 0.15, p = 0.0005), HDL-c (r = 0.13, p = 0.003), fasting insulin (r = 0.12, p = 0.003) and systolic blood pressure (r = 0.11, p with = 0.01). In the multiple linear regression analysis BMI (r = 0.05, p = 0.002), fasting glucose (r = -0.01, p = 0.003) and HDL-c (r = 0.017, p < 0.001) were associated to CRP concentrations after adjusting for the other components of MS. Conclusion: The association found between individual components of MS and CRP concentrations suggests that inflammation might be an early event in the development of metabolic disorders in adolescents.Grupo AránNutrición Hospitalaria v.28 n.5 20132013-10-01journal articletext/htmlhttp://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500032en |
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Leandro da Cruz,Larissa Cardoso,Luciane Daniele Pala,Daniela Paula,Heberth de Alves Lamounier,Joel Mariano Silva,Camilo Adalton Pinheiro Volp,Ana Carolina Nascimento de Freitas,Renata |
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Leandro da Cruz,Larissa Cardoso,Luciane Daniele Pala,Daniela Paula,Heberth de Alves Lamounier,Joel Mariano Silva,Camilo Adalton Pinheiro Volp,Ana Carolina Nascimento de Freitas,Renata Metabolic syndrome components can predict C reactive protein concentration in adolescents |
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Leandro da Cruz,Larissa Cardoso,Luciane Daniele Pala,Daniela Paula,Heberth de Alves Lamounier,Joel Mariano Silva,Camilo Adalton Pinheiro Volp,Ana Carolina Nascimento de Freitas,Renata |
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Leandro da Cruz,Larissa |
title |
Metabolic syndrome components can predict C reactive protein concentration in adolescents |
title_short |
Metabolic syndrome components can predict C reactive protein concentration in adolescents |
title_full |
Metabolic syndrome components can predict C reactive protein concentration in adolescents |
title_fullStr |
Metabolic syndrome components can predict C reactive protein concentration in adolescents |
title_full_unstemmed |
Metabolic syndrome components can predict C reactive protein concentration in adolescents |
title_sort |
metabolic syndrome components can predict c reactive protein concentration in adolescents |
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Background: Metabolic syndrome (MS) is suggested to be associated with a low grade inflammation state, but the relationship between inflammation biomarkers and the components of metabolic syndrome in adolescents are still lacking. Objective: To investigate the association between C-reactive protein (CRP) serum concentrations and metabolic syndrome components in adolescents. Methods: A cross-sectional population based study was conducted. Anthropometric, biochemical and clinical data were collected from 524 adolescents (11-15 years old) randomly sampled from school population of Alegre city, Espmto Santo, Brazil. Data were analyzed by STATA version 9.0. Results: Adolescents with higher values for BMI (p = 0.001) and higher body fat percentage (p = 0.003) had higher CRP concentrations than those with lower BMI and body fat percentage. CRP concentrations was directly correlated with BMI (r = 0.17, p = 0.0001), waist circumference (r = 0.15, p = 0.0005), HDL-c (r = 0.13, p = 0.003), fasting insulin (r = 0.12, p = 0.003) and systolic blood pressure (r = 0.11, p with = 0.01). In the multiple linear regression analysis BMI (r = 0.05, p = 0.002), fasting glucose (r = -0.01, p = 0.003) and HDL-c (r = 0.017, p < 0.001) were associated to CRP concentrations after adjusting for the other components of MS. Conclusion: The association found between individual components of MS and CRP concentrations suggests that inflammation might be an early event in the development of metabolic disorders in adolescents. |
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Grupo Arán |
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2013 |
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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500032 |
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