Nutritional status of iron in children from 6 to 59 months of age and its relation to vitamin A deficiency

Objective: To evaluate the iron nutritional status of children from 6 to 59 months of age and its relation to vitamin A deficiency. Method: Cross-sectional study involving 100 children, living in nine cities in the state of Paraiba, which were selected for convenience to form two study groups: children with vitamin A deficiency (serum retinol < 0.70 &#956;mol/L; n = 50) and children without vitamin A deficiency (serum retinol &gt; 0.70 &#956;mol/L; n = 50). The iron nutritional status was evaluated by biochemical, hematological and hematimetric indices. The cases of subclinical infection (C-Reactive Protein &gt; 6 mg/L) were excluded. Results: Children with vitamin A deficiency had serum iron values statistically lower than the corresponding values in children without deficiency. The other iron nutritional status indices showed no statistical difference according to presence/absence of vitamin A deficiency. Conclusion: The interaction between iron and vitamin A deficiencies was evidenced in the case of circulating iron deficiency (serum iron), suggesting failure in the transport mechanisms of the mineral in children with vitamin A deficiency.

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Bibliographic Details
Main Authors: Sales,Marcia Cristina, Azevedo Paiva,Adriana de, Queiroz,Daiane de, Araújo França Costa,Renata, Lins da Cunha,Maria Auxiliadora, Figueroa Pedraza,Dixis
Format: Digital revista
Language:English
Published: Grupo Arán 2013
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000300027
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Summary:Objective: To evaluate the iron nutritional status of children from 6 to 59 months of age and its relation to vitamin A deficiency. Method: Cross-sectional study involving 100 children, living in nine cities in the state of Paraiba, which were selected for convenience to form two study groups: children with vitamin A deficiency (serum retinol < 0.70 &#956;mol/L; n = 50) and children without vitamin A deficiency (serum retinol &gt; 0.70 &#956;mol/L; n = 50). The iron nutritional status was evaluated by biochemical, hematological and hematimetric indices. The cases of subclinical infection (C-Reactive Protein &gt; 6 mg/L) were excluded. Results: Children with vitamin A deficiency had serum iron values statistically lower than the corresponding values in children without deficiency. The other iron nutritional status indices showed no statistical difference according to presence/absence of vitamin A deficiency. Conclusion: The interaction between iron and vitamin A deficiencies was evidenced in the case of circulating iron deficiency (serum iron), suggesting failure in the transport mechanisms of the mineral in children with vitamin A deficiency.