Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients

Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients

SUMMARY OBJECTIVE: The aim of this retrospective study was to investigate the correlation of transiently elevated postoperative serum cancer antigen 125 levels and prognosis in patients with non-small cell lung cancer. METHODS: A total of 181 non-small cell lung cancer patients with normal levels of preoperative serum cancer antigen 125 were statistically summarized in this study. RESULTS: Out of the analyzed patients, 22 (12.2%) showed elevation of serum cancer antigen 125 within one month after surgery. Serum cancer antigen 125 level decreased to normal at three months postoperation. Serum cancer antigen 125 was positively correlated with pro-brain natriuretic peptide in non-small cell lung cancer postoperative patients (p=0.00035). Univariate analysis did not find significant difference in disease progression survival between those who experienced cancer antigen 125 elevation in the early postoperation and those who did not (p=0.646). CONCLUSIONS: In conclusion, transient elevation of cancer antigen 125 is associated to pro-brain natriuretic peptide increase after pulmonary surgery in non-small cell lung cancer patients.

Saved in:
Bibliographic Details
Main Author: Ye,Yiwang
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000100039
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S0104-42302021000100039
record_format ojs
spelling oai:scielo:S0104-423020210001000392021-06-16Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patientsYe,Yiwang Carcinoma, non-small-cell lung CA-125 antigens Biomarkers Neoplasms Natriuretic peptide, brain SUMMARY OBJECTIVE: The aim of this retrospective study was to investigate the correlation of transiently elevated postoperative serum cancer antigen 125 levels and prognosis in patients with non-small cell lung cancer. METHODS: A total of 181 non-small cell lung cancer patients with normal levels of preoperative serum cancer antigen 125 were statistically summarized in this study. RESULTS: Out of the analyzed patients, 22 (12.2%) showed elevation of serum cancer antigen 125 within one month after surgery. Serum cancer antigen 125 level decreased to normal at three months postoperation. Serum cancer antigen 125 was positively correlated with pro-brain natriuretic peptide in non-small cell lung cancer postoperative patients (p=0.00035). Univariate analysis did not find significant difference in disease progression survival between those who experienced cancer antigen 125 elevation in the early postoperation and those who did not (p=0.646). CONCLUSIONS: In conclusion, transient elevation of cancer antigen 125 is associated to pro-brain natriuretic peptide increase after pulmonary surgery in non-small cell lung cancer patients.info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.67 n.1 20212021-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000100039en10.1590/1806-9282.67.01.20200102
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Ye,Yiwang
spellingShingle Ye,Yiwang
Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
author_facet Ye,Yiwang
author_sort Ye,Yiwang
title Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
title_short Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
title_full Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
title_fullStr Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
title_full_unstemmed Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
title_sort postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
description SUMMARY OBJECTIVE: The aim of this retrospective study was to investigate the correlation of transiently elevated postoperative serum cancer antigen 125 levels and prognosis in patients with non-small cell lung cancer. METHODS: A total of 181 non-small cell lung cancer patients with normal levels of preoperative serum cancer antigen 125 were statistically summarized in this study. RESULTS: Out of the analyzed patients, 22 (12.2%) showed elevation of serum cancer antigen 125 within one month after surgery. Serum cancer antigen 125 level decreased to normal at three months postoperation. Serum cancer antigen 125 was positively correlated with pro-brain natriuretic peptide in non-small cell lung cancer postoperative patients (p=0.00035). Univariate analysis did not find significant difference in disease progression survival between those who experienced cancer antigen 125 elevation in the early postoperation and those who did not (p=0.646). CONCLUSIONS: In conclusion, transient elevation of cancer antigen 125 is associated to pro-brain natriuretic peptide increase after pulmonary surgery in non-small cell lung cancer patients.
publisher Associação Médica Brasileira
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000100039
work_keys_str_mv AT yeyiwang postoperativetransientelevationofserumcancerantigen125innonsmallcelllungcancerpatients
_version_ 1756410101048016896

Similar Items