Primary infratentorial diffuse large b-cell lymphoma: a challenging diagnosis in an immunocompetent patient

SUMMARY We describe the case of a female patient, 52 years old, with dizziness and left motor incoordination for 2 weeks. Brain MRI magnetic resonance imaging) revealed a hyperintense lesion on T2-weighted images, without restricted diffusion, in the left middle cerebellar peduncle. Spectroscopy demonstrated peak of lipids and perfusion did not show any elevation in relative cerebral blood volume (rCBV). The patient underwent an open biopsy and resection, and the diagnosis of diffuse large B-cell lymphoma (DLBCL) was established. The patient received intravenous dexamethasone with symptoms remission, followed by four cycles of methotrexate plus cytarabine. After 3 months, the patient returned with decreased consciences level and a new MRI revealed a right superior frontal gyrus lesion with features suggesting a lymphomatous lesion. The patient died five days after her relapse.

Bibliographic Details

Main Authors:	Beraldo,Gabriel Laverdi, Brito,Angelo Borsarelli Carvalho, Delamain,Márcia Torresan, Souza,Carmino Antonio de, Lima,Carmen Silvia Passos, Bonfitto,João Felipe Leite, Queiroz,Luciano de Souza, Reis,Fabiano
Format:	Digital revista
Language:	English
Published:	Associação Médica Brasileira 2019
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302019000200136
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