Adhesion molecules in breast carcinoma: a challenge to the pathologist

The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate tumors and further classify them according to a molecular point of view. Our goal is to describe the applicability and the difficulties encountered by the pathologist in the diagnosis of breast carcinoma, discussing the most commonly used markers of adhesion in routine analyses.

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Main Authors: Rossetti,Claudia, Reis,Beatriz da Costa Aguiar Alves, Delgado,Pamela de Oliveira, Azzalis,Ligia Ajaime, Junqueira,Virginia B. C., Feder,David, Fonseca,Fernando
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000100020
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spelling oai:scielo:S0104-423020150001000202015-07-27Adhesion molecules in breast carcinoma: a challenge to the pathologistRossetti,ClaudiaReis,Beatriz da Costa Aguiar AlvesDelgado,Pamela de OliveiraAzzalis,Ligia AjaimeJunqueira,Virginia B. C.Feder,DavidFonseca,Fernando cell adhesion molecules junctional adhesion molecules breast neoplasms The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate tumors and further classify them according to a molecular point of view. Our goal is to describe the applicability and the difficulties encountered by the pathologist in the diagnosis of breast carcinoma, discussing the most commonly used markers of adhesion in routine analyses.info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.61 n.1 20152015-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000100020en10.1590/1806-9282.61.01.081
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libraryname SciELO
language English
format Digital
author Rossetti,Claudia
Reis,Beatriz da Costa Aguiar Alves
Delgado,Pamela de Oliveira
Azzalis,Ligia Ajaime
Junqueira,Virginia B. C.
Feder,David
Fonseca,Fernando
spellingShingle Rossetti,Claudia
Reis,Beatriz da Costa Aguiar Alves
Delgado,Pamela de Oliveira
Azzalis,Ligia Ajaime
Junqueira,Virginia B. C.
Feder,David
Fonseca,Fernando
Adhesion molecules in breast carcinoma: a challenge to the pathologist
author_facet Rossetti,Claudia
Reis,Beatriz da Costa Aguiar Alves
Delgado,Pamela de Oliveira
Azzalis,Ligia Ajaime
Junqueira,Virginia B. C.
Feder,David
Fonseca,Fernando
author_sort Rossetti,Claudia
title Adhesion molecules in breast carcinoma: a challenge to the pathologist
title_short Adhesion molecules in breast carcinoma: a challenge to the pathologist
title_full Adhesion molecules in breast carcinoma: a challenge to the pathologist
title_fullStr Adhesion molecules in breast carcinoma: a challenge to the pathologist
title_full_unstemmed Adhesion molecules in breast carcinoma: a challenge to the pathologist
title_sort adhesion molecules in breast carcinoma: a challenge to the pathologist
description The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate tumors and further classify them according to a molecular point of view. Our goal is to describe the applicability and the difficulties encountered by the pathologist in the diagnosis of breast carcinoma, discussing the most commonly used markers of adhesion in routine analyses.
publisher Associação Médica Brasileira
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000100020
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AT reisbeatrizdacostaaguiaralves adhesionmoleculesinbreastcarcinomaachallengetothepathologist
AT delgadopameladeoliveira adhesionmoleculesinbreastcarcinomaachallengetothepathologist
AT azzalisligiaajaime adhesionmoleculesinbreastcarcinomaachallengetothepathologist
AT junqueiravirginiabc adhesionmoleculesinbreastcarcinomaachallengetothepathologist
AT federdavid adhesionmoleculesinbreastcarcinomaachallengetothepathologist
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