Adhesion molecules in breast carcinoma: a challenge to the pathologist
The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate tumors and further classify them according to a molecular point of view. Our goal is to describe the applicability and the difficulties encountered by the pathologist in the diagnosis of breast carcinoma, discussing the most commonly used markers of adhesion in routine analyses.
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Associação Médica Brasileira
2015
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oai:scielo:S0104-423020150001000202015-07-27Adhesion molecules in breast carcinoma: a challenge to the pathologistRossetti,ClaudiaReis,Beatriz da Costa Aguiar AlvesDelgado,Pamela de OliveiraAzzalis,Ligia AjaimeJunqueira,Virginia B. C.Feder,DavidFonseca,Fernando cell adhesion molecules junctional adhesion molecules breast neoplasms The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate tumors and further classify them according to a molecular point of view. Our goal is to describe the applicability and the difficulties encountered by the pathologist in the diagnosis of breast carcinoma, discussing the most commonly used markers of adhesion in routine analyses.info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.61 n.1 20152015-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000100020en10.1590/1806-9282.61.01.081 |
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Rossetti,Claudia Reis,Beatriz da Costa Aguiar Alves Delgado,Pamela de Oliveira Azzalis,Ligia Ajaime Junqueira,Virginia B. C. Feder,David Fonseca,Fernando |
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Rossetti,Claudia Reis,Beatriz da Costa Aguiar Alves Delgado,Pamela de Oliveira Azzalis,Ligia Ajaime Junqueira,Virginia B. C. Feder,David Fonseca,Fernando Adhesion molecules in breast carcinoma: a challenge to the pathologist |
author_facet |
Rossetti,Claudia Reis,Beatriz da Costa Aguiar Alves Delgado,Pamela de Oliveira Azzalis,Ligia Ajaime Junqueira,Virginia B. C. Feder,David Fonseca,Fernando |
author_sort |
Rossetti,Claudia |
title |
Adhesion molecules in breast carcinoma: a challenge to the pathologist |
title_short |
Adhesion molecules in breast carcinoma: a challenge to the pathologist |
title_full |
Adhesion molecules in breast carcinoma: a challenge to the pathologist |
title_fullStr |
Adhesion molecules in breast carcinoma: a challenge to the pathologist |
title_full_unstemmed |
Adhesion molecules in breast carcinoma: a challenge to the pathologist |
title_sort |
adhesion molecules in breast carcinoma: a challenge to the pathologist |
description |
The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate tumors and further classify them according to a molecular point of view. Our goal is to describe the applicability and the difficulties encountered by the pathologist in the diagnosis of breast carcinoma, discussing the most commonly used markers of adhesion in routine analyses. |
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Associação Médica Brasileira |
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2015 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000100020 |
work_keys_str_mv |
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_version_ |
1756409923246227456 |