Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature

ABSTRACT Objectives: to obtain information from scientific literature concerning infusion pumps used in administering erythrocyte (red blood cells) and to evaluate the implications in the practical use of this equipment by nurses when conducting transfusions. Method: an integrative revision of the following scientific databases: Pubmed/Medline, Scopus, the Virtual Library for Health, SciELO, Web of Science and Cochrane. The following descriptors were used: "infusion pumps", "blood transfusion", "transfused erythrocyte" and "hemolyis". There were no restrictions on the scope of the initial data and it was finalized in December 2014. 17 articles were identified in accordance with the inclusion and exclusion criteria. Results: all of the publications included in the studies were experimental in vitro and covered the use of infusion pumps in transfusion therapy. A summary of the data was presented in a synoptic chart and an analysis of it generated the following categories: cellular damage and the infusion mechanism. Conclusion: infusion pumps can be harmful to erythrocytes based on the infusion mechanism that is used, as the linear peristaltic pump is more likely to cause hemolysis. Cellular damage is related to the plasmatic liberation of markers that largely dominate free hemoglobin and potassium. We reiterate the need for further research and technological investments to guide the development of protocols that promote safe practices and that can contribute to future clinical studies.

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Main Authors: Wilson,Ana Maria Miranda Martins, Peterlini,Maria Angélica Sorgini, Pedreira,Mavilde da Luz Gonçalves
Format: Digital revista
Language:English
Published: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-11692016000100607
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spelling oai:scielo:S0104-116920160001006072016-08-22Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literatureWilson,Ana Maria Miranda MartinsPeterlini,Maria Angélica SorginiPedreira,Mavilde da Luz Gonçalves Nursing Infusion Pumps Erythrocytes Hemolysis ABSTRACT Objectives: to obtain information from scientific literature concerning infusion pumps used in administering erythrocyte (red blood cells) and to evaluate the implications in the practical use of this equipment by nurses when conducting transfusions. Method: an integrative revision of the following scientific databases: Pubmed/Medline, Scopus, the Virtual Library for Health, SciELO, Web of Science and Cochrane. The following descriptors were used: "infusion pumps", "blood transfusion", "transfused erythrocyte" and "hemolyis". There were no restrictions on the scope of the initial data and it was finalized in December 2014. 17 articles were identified in accordance with the inclusion and exclusion criteria. Results: all of the publications included in the studies were experimental in vitro and covered the use of infusion pumps in transfusion therapy. A summary of the data was presented in a synoptic chart and an analysis of it generated the following categories: cellular damage and the infusion mechanism. Conclusion: infusion pumps can be harmful to erythrocytes based on the infusion mechanism that is used, as the linear peristaltic pump is more likely to cause hemolysis. Cellular damage is related to the plasmatic liberation of markers that largely dominate free hemoglobin and potassium. We reiterate the need for further research and technological investments to guide the development of protocols that promote safe practices and that can contribute to future clinical studies.info:eu-repo/semantics/openAccessEscola de Enfermagem de Ribeirão Preto / Universidade de São PauloRevista Latino-Americana de Enfermagem v.24 20162016-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-11692016000100607en10.1590/1518-8345.1155.2763
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Wilson,Ana Maria Miranda Martins
Peterlini,Maria Angélica Sorgini
Pedreira,Mavilde da Luz Gonçalves
spellingShingle Wilson,Ana Maria Miranda Martins
Peterlini,Maria Angélica Sorgini
Pedreira,Mavilde da Luz Gonçalves
Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
author_facet Wilson,Ana Maria Miranda Martins
Peterlini,Maria Angélica Sorgini
Pedreira,Mavilde da Luz Gonçalves
author_sort Wilson,Ana Maria Miranda Martins
title Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
title_short Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
title_full Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
title_fullStr Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
title_full_unstemmed Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
title_sort infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature
description ABSTRACT Objectives: to obtain information from scientific literature concerning infusion pumps used in administering erythrocyte (red blood cells) and to evaluate the implications in the practical use of this equipment by nurses when conducting transfusions. Method: an integrative revision of the following scientific databases: Pubmed/Medline, Scopus, the Virtual Library for Health, SciELO, Web of Science and Cochrane. The following descriptors were used: "infusion pumps", "blood transfusion", "transfused erythrocyte" and "hemolyis". There were no restrictions on the scope of the initial data and it was finalized in December 2014. 17 articles were identified in accordance with the inclusion and exclusion criteria. Results: all of the publications included in the studies were experimental in vitro and covered the use of infusion pumps in transfusion therapy. A summary of the data was presented in a synoptic chart and an analysis of it generated the following categories: cellular damage and the infusion mechanism. Conclusion: infusion pumps can be harmful to erythrocytes based on the infusion mechanism that is used, as the linear peristaltic pump is more likely to cause hemolysis. Cellular damage is related to the plasmatic liberation of markers that largely dominate free hemoglobin and potassium. We reiterate the need for further research and technological investments to guide the development of protocols that promote safe practices and that can contribute to future clinical studies.
publisher Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-11692016000100607
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