Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle

ABSTRACT: This report provides an unpublished account of an intra-abdominal myolipoma in a 11-year-old female Poodle with hyperadrenocorticism and diabetes mellitus. The patient was well controlled for both endocrine diseases; however, was suffering for severe abdominal discomfort. Ultrasound scan revealed a huge abdominal mass. At necropsy a pinkish mass (35cm x 28cm x 12cm) of elastic consistency attached to the broad ligament of the left uterine horn was reported. Histologically, this mass was constituted of a mixed population of well-differentiated adipocytes and of spindle-shaped mesenchymal cells. Both tumor cells were positive for vimentin at immunohistochemistry, while the spindle-shaped cells were positive for desmin and actin, compatible with smooth muscle cells. Immunohistochemistry was crucial for myolipoma characterization.

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Main Authors: Pöppl,Alan Gomes, Beck,Carlos Afonso de Castro, Fonini,Alessandra Van Der Laan, Cruz,Leonardo Montagna, Pavarini,Saulo Petinati
Format: Digital revista
Language:English
Published: Universidade Federal de Santa Maria 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000550
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spelling oai:scielo:S0103-847820180010005502018-10-09Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodlePöppl,Alan GomesBeck,Carlos Afonso de CastroFonini,Alessandra Van Der LaanCruz,Leonardo MontagnaPavarini,Saulo Petinati dog abdominal tumors Cushing’s syndrome immunohistochemistry ABSTRACT: This report provides an unpublished account of an intra-abdominal myolipoma in a 11-year-old female Poodle with hyperadrenocorticism and diabetes mellitus. The patient was well controlled for both endocrine diseases; however, was suffering for severe abdominal discomfort. Ultrasound scan revealed a huge abdominal mass. At necropsy a pinkish mass (35cm x 28cm x 12cm) of elastic consistency attached to the broad ligament of the left uterine horn was reported. Histologically, this mass was constituted of a mixed population of well-differentiated adipocytes and of spindle-shaped mesenchymal cells. Both tumor cells were positive for vimentin at immunohistochemistry, while the spindle-shaped cells were positive for desmin and actin, compatible with smooth muscle cells. Immunohistochemistry was crucial for myolipoma characterization.info:eu-repo/semantics/openAccessUniversidade Federal de Santa MariaCiência Rural v.48 n.10 20182018-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000550en10.1590/0103-8478cr20180344
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libraryname SciELO
language English
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author Pöppl,Alan Gomes
Beck,Carlos Afonso de Castro
Fonini,Alessandra Van Der Laan
Cruz,Leonardo Montagna
Pavarini,Saulo Petinati
spellingShingle Pöppl,Alan Gomes
Beck,Carlos Afonso de Castro
Fonini,Alessandra Van Der Laan
Cruz,Leonardo Montagna
Pavarini,Saulo Petinati
Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
author_facet Pöppl,Alan Gomes
Beck,Carlos Afonso de Castro
Fonini,Alessandra Van Der Laan
Cruz,Leonardo Montagna
Pavarini,Saulo Petinati
author_sort Pöppl,Alan Gomes
title Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
title_short Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
title_full Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
title_fullStr Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
title_full_unstemmed Myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
title_sort myolipoma associated with hyperadrenocorticism and diabetes mellitus in a female poodle
description ABSTRACT: This report provides an unpublished account of an intra-abdominal myolipoma in a 11-year-old female Poodle with hyperadrenocorticism and diabetes mellitus. The patient was well controlled for both endocrine diseases; however, was suffering for severe abdominal discomfort. Ultrasound scan revealed a huge abdominal mass. At necropsy a pinkish mass (35cm x 28cm x 12cm) of elastic consistency attached to the broad ligament of the left uterine horn was reported. Histologically, this mass was constituted of a mixed population of well-differentiated adipocytes and of spindle-shaped mesenchymal cells. Both tumor cells were positive for vimentin at immunohistochemistry, while the spindle-shaped cells were positive for desmin and actin, compatible with smooth muscle cells. Immunohistochemistry was crucial for myolipoma characterization.
publisher Universidade Federal de Santa Maria
publishDate 2018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000550
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